Oxidative amination of heteroaromatic zinc reagents mediated by PhI(OAc)(2).

Org Lett

Department Chemie & Biochemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377, München, Germany.

Published: November 2009

AI Article Synopsis

  • The oxidative amination process for functionalized heterocycles has been successfully conducted using common heterocyclic zinc compounds and lithium amides.
  • PhI(OAc)(2) has been identified as an effective reagent for facilitating this oxidative amination reaction.
  • This method highlights a practical approach for modifying heterocycles, which could be useful in various organic chemistry applications.

Article Abstract

The oxidative amination of functionalized heterocycles has been achieved by using readily available heterocyclic zinc reagents and lithium amides. PhI(OAc)(2) proved to be a suitable reagent for this oxidative amination.

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Source
http://dx.doi.org/10.1021/ol902056jDOI Listing

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