Non-steroidal anti-inflammatory drugs in orthopaedic and perioperative practice.

J Perioper Pract

Academic Orthopaedic Registrar, University College London Institute of Orthopaedic and Musculoskeletal Research, Royal National Orthopaedic Hospital, Stanmore, Middlesex HA7 4LP, UK.

Published: September 2009

AI Article Synopsis

  • Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for pain relief, inflammation reduction, and fever management, especially in orthopaedic and surgical settings.
  • Despite their effectiveness, NSAIDs carry serious side effects that can be life-threatening, which requires careful consideration before use.
  • Research indicates that NSAIDs may negatively impact bone formation, raising concerns about their safety for patients with fractures or other bone-related conditions.

Article Abstract

Non-steroidal anti-inflammatory drugs are powerful and effective anti-inflammatory, analgesic and anti-pyretic drugs. They are routinely used in orthopaedic conditions and in the perioperative setting. They are however associated with potentially life-threatening side-effects and it is important to appreciate these before these medicines are administered. There is evidence suggesting that these drugs adversely affect bone formation, and this has implications for their use in patients with fractures and other pathologies that involve bone remodelling.

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Source
http://dx.doi.org/10.1177/175045890901900903DOI Listing

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