Objectives: Laparoscopic herniorrhaphy employing non-absorbable mesh (LMH) is a frequently performed procedure for groin hernia. Multiple case reports in the urologic literature have identified LMH as a complicating factor in patients undergoing open radical retropubic prostatectomy (RRP) for prostate cancer. The purpose of this study was to review our experience and outcomes in patients with a prior LMH undergoing open RRP.
Methods: After institutional review board approval, a retrospective review of all open RRPs performed by a single surgeon between 2003 and 2008 was used to identify patients with a history of a prior LMH. The outcomes of these patients were compared with a contemporary cohort of patients undergoing RRP by the same surgeon.
Results: Eighteen patients with a prior LMH underwent RRP. Five of the 18 had bilateral LMH, with unilateral LMH in the remainder. Outcomes in this group were compared with 38 patients without prior LMH. There was no difference between the groups in terms of age, preoperative PSA, prostate size, preoperative Gleason score, or body mass index, and RRP was successfully performed in all 18 LMH patients. One of 18 patients had a postoperative complication (persistent JP drainage). Compared with the control group, differences in operative time and blood loss bordered on statistical significance.
Conclusions: Prior LMH is not a contraindication to RRP. While resulting in slightly longer operating times and higher blood loss, our experience suggests that RRP can be safely performed in these patients.
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http://dx.doi.org/10.1016/j.urolonc.2009.06.006 | DOI Listing |
J Pain Symptom Manage
September 2024
Department of Anesthesiology (R.A.), Larner College of Medicine at the University of Vermont, Burlington, Vermont, USA.
Context: Though patients undergoing treatment for upper gastrointestinal (GI) cancers frequently experience a range of sequelae and disease recurrence, patients often do not receive specialty palliative care soon after diagnosis and it is unknown in what ways they may benefit.
Objectives: To understand patient experiences of specialty palliative care in the perioperative period for patients seeking curative intent upper GI oncologic surgery.
Methods: As part of a randomized controlled trial, we conducted in-depth interviews between November 2019 and July 2021 with 23 patients in the intervention arm who were undergoing curative intent treatment for upper GI cancers and who were also followed by the specialty palliative care team.
Parasit Vectors
October 2023
Vector Control Product Testing Unit (VCPTU), Environmental Health and Ecological Sciences, Ifakara Health Institute, P.O. Box 74, Bagamoyo, Tanzania.
Background: Pyrethroid resistance in the key malaria vectors threatens the success of pyrethroid-treated nets. To overcome pyrethroid resistance, Interceptor G2 (IG2), a 'first-in-class' dual insecticidal net that combines alpha-cypermethrin with chlorfenapyr, was developed. Chlorfenapyr is a pro-insecticide, requiring bio-activation by oxidative metabolism within the insect's mitochondria, constituting a mode of action preventing cross-resistance to pyrethroids.
View Article and Find Full Text PDFRadiology
June 2023
From the Departments of Surgery (B.L.S.) and Radiology (B.L.S., S.D.H.), University of Vermont Cancer Center, University of Vermont Larner College of Medicine, UHC Bldg, Room 4425, 1 S Prospect St, Burlington, VT 05401; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, Wash (R.Y.C., Y.R.S., E.J.A.B., D.L.M.); Department of Radiology, University of Washington, Fred Hutchinson Cancer Center, Seattle, Wash (K.P.L., C.I.L.); Departments of Medicine and Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, Calif (K.K.); Department of Radiology, University of North Carolina, Chapel Hill, NC (L.M.H.); Department of Population Health Sciences, University of Utah, Huntsman Cancer Institute, Salt Lake City, Utah (T.O.); Department of Radiology, Giesel School of Medicine at Dartmouth, Lebanon, NH (R.M.d.F.A.); and Division of Biostatistics, Department of Public Health Sciences, University of California-Davis, Davis, Calif (D.L.M.).
Background Prior cross-sectional studies have observed that breast cancer screening with digital breast tomosynthesis (DBT) has a lower recall rate and higher cancer detection rate compared with digital mammography (DM). Purpose To evaluate breast cancer screening outcomes with DBT versus DM on successive screening rounds. Materials and Methods In this retrospective cohort study, data from 58 breast imaging facilities in the Breast Cancer Surveillance Consortium were collected.
View Article and Find Full Text PDFRadiology
May 2023
From the Department of Radiology, University of Washington School of Medicine, Hutchinson Institute for Cancer Outcomes Research, Fred Hutchinson Cancer Center, 825 Eastlake Ave E, LG-200, Seattle, WA 98109 (C.I.L., J.M.L.); Department of Health Systems & Population Health, University of Washington School of Public Health, Seattle, Wash (C.I.L.); Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, Wash (C.I.L., L.A., D.L.M., J.M.L., E.J.A.B.); Division of Biostatistics, Department of Public Health Sciences, University of California Davis School of Medicine, Davis, Calif (D.L.M.); Department of Population Health Sciences, and the Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah (T.O.); Department of Medicine, Department of Epidemiology and Biostatistics, and General Internal Medicine Section, Department of Veterans Affairs, University of California, San Francisco, San Francisco, Calif (K.K.); Department of Surgery, Office of Health Promotion Research, Larner College of Medicine at the University of Vermont and University of Vermont Cancer Center, Burlington, Vt (B.L.S.); The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth and Norris Cotton Cancer Center, Lebanon, NH (A.N.A.T.); Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Ill (G.H.R.); Department of Radiology, Geisel School of Medicine at Dartmouth, Lebanon, NH (R.M.d.A.); and Department of Radiology, University of North Carolina, Chapel Hill, NC (L.M.H.).
Background It is important to establish screening mammography performance benchmarks for quality improvement efforts. Purpose To establish performance benchmarks for digital breast tomosynthesis (DBT) screening and evaluate performance trends over time in U.S.
View Article and Find Full Text PDFAm Heart J
August 2023
Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Background: Acute kidney injury (AKI), including contrast-induced AKI (CI-AKI), is an important complication of percutaneous coronary intervention (PCI), resulting in short- and long-term adverse clinical outcomes. While prior research has reported an increased cost burden to hospitals from CI-AKI, the incremental cost to payers remains unknown. Understanding this incremental cost may inform decisions and even policy in the future.
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