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Infectious intestinal diseases elevate neurodegenerative disease risk based on a nationwide population-based cohort study.
Sci Rep
December 2024
Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Infectious intestinal diseases (IIDs) pose a significant health and economic burden worldwide. Recent observations at the Tri-Service General Hospital, Taiwan, suggest a potential association between IIDs and neurodegenerative diseases, prompting an investigation into this relationship. This study explored interactions between IIDs and neurodegenerative diseases.
View Article and Find Full Text PDFAllogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial (phase II).
PLoS One
December 2024
The Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Background: Exposure of critically ill patients to antibiotics lead to intestinal dysbiosis, which often manifests as antibiotic-associated diarrhoea. Faecal microbiota transplantation restores gut microbiota and may lead to faster resolution of diarrhoea.
Methods: Into this prospective, multi-centre, randomized controlled trial we will enrol 36 critically ill patients with antibiotic-associated diarrhoea.
Preoperative Albumin to Alkaline Phosphatase Ratio and Inflammatory Burden Index for Rectal Cancer Prognostic Nomogram-Construction: Based on Multiple Machine Learning.
J Inflamm Res
December 2024
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Soochow University, Suzhou City, Jiangsu Province, People's Republic of China.
Purpose: Preoperative albumin to alkaline phosphatase ratio (AAPR) and inflammatory burden index (IBI) are prognostic indicators for a multitude of cancers, and our study focuses on evaluating the prognostic significance of the AAPR and the IBI on rectal cancer (RC) patients to provide a more accurate guideline for patient prognosis.
Patients And Methods: This study enrolled patients who underwent laparoscopic rectal cancer surgery from January 2016 to January 2021. We utilized three machine learning approaches to select variables most relevant to prognosis in the training cohort.
[Several problems needing attention in the diagnosis and treatment of common perianal benign diseases].
Zhonghua Wei Chang Wai Ke Za Zhi
December 2024
the 989th Hospital of the Joint Service Support Force of the Chinese People's Liberation Army / Research Institute of Anorectal Surgery of the Chinese People's Liberation Army, Luoyang471000, China.
Hemorrhoids, anal fissure, anal fistula and perianal abscess are the most common benign diseases around the anus, which obviously affect people's life and work, and need to be well diagnosed and treated. Based on damage control, the treatment principle is to eliminate relevant disease symptoms and protect the anal function at the same time. Perianal benign diseases are common and frequently occurring, which can be diagnosed and treated in many non-specialist hospitals.
View Article and Find Full Text PDFMycotic aneurysm due to Magnusiomyces capitatus complicating a second liver transplant in a colonized patient.
Int J Infect Dis
December 2024
Institut des Agents Infectieux, Laboratoire de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Lyon, France.; UR 3738-CICLY-Equipe Inflammation et Immunité de L'épithélium Respiratoire, Faculté de Médecine Lyon-Sud Charles Mérieux, Université Claude Bernard Lyon 1, Lyon, France.. Electronic address:
This report presents an extremely rare case of fungal mycotic aneurysm due to Magnusiomyces capitatus in a 51-year-old immunocompromised woman. The diagnosis was based on multiple CT-scans and various samples positive for the pathogen identified by sequencing of the Internal Transcribed Spacer region. Long-term treatment using caspofungin for previous candidemia would have promoted the dissemination of this intrinsically echinocandin-resistant fungus, from colonization sites in the lung and rectal areas.
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