Study Objective: To compare the influence of baricity and patient positioning during onset of subarachnoid block in patients placed in the prone, jackknife position with head-down tilt of 15 degrees .
Design: Randomized study.
Setting: Operating room of Tonami General Hospital.
Patients: 180 ASA physical I and II patients (134 men and 46 women), aged 18 to 54 years, scheduled for elective perianal surgery.
Interventions: Patients were randomly divided into 6 groups (n = 30 each) based on baricity (hyperbaric or isobaric) of 0.5% bupivacaine (5 mg) and duration of the sitting position (two, 5, or 10 min) after injection.
Measurements: Sensory block levels were examined by pinprick at 0, 5, 10, 20, and 60 minutes after jackknife positioning. Systolic blood pressure and heart rate were also recorded.
Main Results: After jackknife positioning, sensory block levels progressively increased until 15 or 20 minutes in all groups. Regardless of baricity of bupivacaine, sensory block levels were higher at 10 through 60 minutes in the two-minute sitting groups than in the 5-minute or 10-minute sitting groups (P < 0.01 and P < 0.01, respectively), and in the 5-minute sitting groups than in the 10-minute sitting groups (P < 0.05). The mean highest sensory block levels were T5, T9, and T11 in the two-minute, 5-minute, and 10-minute sitting groups, respectively.
Conclusion: Patient positioning, not baricity of bupivacaine, significantly affected the cephalad spread of spinal anesthesia, and a 10-minute period in the sitting position limits the maximum cephalad spread to T11.
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http://dx.doi.org/10.1016/j.jclinane.2008.11.008 | DOI Listing |
Int Arch Occup Environ Health
January 2025
Division of Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Nöldnerstr. 40-42, 10317, Berlin, Germany.
Purpose: This study analyzed longitudinal data to examine whether occupational sitting time is associated with increases in body mass index (BMI) and five-year cardiovascular disease (CVD) risk.
Methods: We included 2,000 employed men and women (aged 31-60) from the German Study on Mental Health at Work (S-MGA) for a BMI analysis and 1,635 participants free of CVD at baseline (2011/2012) for a CVD analysis. Occupational sitting time was categorized into five groups (< 5, 5 to < 15, 15 to < 25, 25 to < 35, and ≥ 35 h per week).
Front Physiol
January 2025
School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Purpose: While it is common practice for schools across the United States to include neurodivergent children in physical education classes, many programs outside of school-such as those at home or in the community-are not effectively tailored to meet their support needs. This gap contributes to lower levels of physical activity among neurodivergent children. Our objective was to address this issue by systematically adapting the program to enable neurodivergent children to safely engage in physical activity at home.
View Article and Find Full Text PDFFront Physiol
January 2025
Environmental Physiology Group, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.
Background And Aim: Hyperventilation before breath-hold diving (freediving) is widely accepted as a risk factor for hypoxic syncope or blackout (BO), but there is no practical way to address it before dives. This study explores the feasibility of using a force sensor to predict end-tidal carbon dioxide ( CO) to assess hyperventilation in freedivers.
Methods And Results: Twenty-one freedivers volunteered to participate during two national competitions.
Mult Scler
January 2025
NYU MS Comprehensive Care Center, Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA.
Background: In the DISCOMS (DISCOntinuation of disease-modifying therapies (DMTs) in multiple sclerosis (MS)) randomized clinical trial, we could not demonstrate that discontinuing MS DMTs in older, stable adults was not inferior to continuing DMTs. Relapses were rare in both groups, and most new disease activity was one to two new brain magnetic resonance imaging (MRI) lesions unassociated with clinical changes.
Objective/aims: Describe results of the DISCOMS extension study.
J Phys Act Health
January 2025
Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), UE3533, Clermont Auvergne University, Aubiere, France.
Background: Active breaks and very low- to low-intensity exercises such as walking or cycling at an active desk have been shown to significantly counteract the negative effect of prolonged sedentary behaviors. The objective was to investigate the effect of physical activity level (PAL) on changes in energy expenditure (EE), heart rate, and substrate oxidation from sit-to-stand and sit-to-light cycling.
Methods: Fifty healthy young males and females (age: 23.
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