Chiral biphenylamide derivative: an efficient organocatalyst for the enantioselective synthesis of alpha-hydroxy phosphonates.

Org Biomol Chem

Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.

Published: November 2009

The aldol reactions of alpha-keto phosphonates and aldehydes were facilitated by an axially chiral biphenylprolinamide under mild conditions, affording the synthetically and pharmaceutically useful products in high yields and excellent enantioselectivities.

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Source
http://dx.doi.org/10.1039/b917554gDOI Listing

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