Gestational hyperlipidemic pancreatitis is an uncommon complication of pregnancy that incurs a high risk of morbidity and mortality of both maternal and fetal patients. We described the response of continous renal replacement therapy in a woman with extreme gestational hyperlipidemia and severe pancreatitis. Five consecutive plasma exchanges didn't lead to a remarkable reduction (10.4% and 4.8%, for the first and fourth times, respectively) at triglyceride levels as the literatures have reported, which reveals that plasma exchange and continous veno-venous heamofiltration may be importment, instead of crucial methods in dealing with gestational hyperlipidemic pancreatitis.
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