Arthrofibrosis is a relatively common complication after total knee arthroplasty that negatively affects function and quality of life. Static progressive stretching is a technique that has shown promising results in the treatment of contractures of the elbow, ankle, wrist and knee. This study evaluated a static progressive stretching device as a treatment method for patients who had refractory knee stiffness after total knee arthroplasty. Twenty-five patients who had knee stiffness and no improvement with conventional physical therapy modalities were treated with the device. After a median of 7 weeks (range, 3-16 weeks), the median increase in range of motion was 25 degrees (range, 8-82 degrees). The median gain in knee active flexion was 19 degrees (range, 5-80 degrees). Ninety-two percent of patients were satisfied with the results. The authors believe static progressive stretching devices may be an effective method for increasing the ranges of motion and satisfaction levels of patients who develop arthrofibrosis after total knee arthroplasty.
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http://dx.doi.org/10.1007/s00167-009-0947-1 | DOI Listing |
Indian J Endocrinol Metab
December 2024
Department of Nuclear Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Introduction: Functioning neuroendocrine tumors (NETs) that do not respond to standard therapies are commonly considered for Peptide Receptor Radionuclide Therapy (PRRT). The benefit of Lu-DOTATATE PRRT in patients with progressive metastatic NET was analyzed and survival in multi-organ involvement.
Methods: Forty-one patients with refractory, progressive, or advanced symptomatic NETs, with or without previous treatment modalities were studied.
Nat Commun
January 2025
University of Strasbourg and CNRS, CESQ and ISIS (UMR 7006), aQCess, 67000, Strasbourg, France.
High-rate quantum error correcting (QEC) codes with moderate overheads in qubit number and control complexity are highly desirable for achieving fault-tolerant quantum computing. Recently, quantum error correction has experienced significant progress both in code development and experimental realizations, with neutral atom qubit architecture rapidly establishing itself as a leading platform in the field. Scalable quantum computing will require processing with QEC codes that have low qubit overhead and large error suppression, and while such codes do exist, they involve a degree of non-locality that has yet to be integrated into experimental platforms.
View Article and Find Full Text PDFMathematical modeling of somatic evolution, a process impacting both host cells and microbial communities in the human body, can capture important dynamics driving carcinogenesis. Here we considered models for esophageal adenocarcinoma (EAC), a cancer that has dramatically increased in incidence over the past few decades in Western populations, with high case fatality rates due to late-stage diagnoses. Despite advancements in genomic analyses of the precursor Barrett's esophagus (BE), prevention of late-stage EAC remains a significant clinical challenge.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Psychology, Università degli Studi della Campania "L. Vanvitelli", 81100 Caserta, Italy.
Mental representation of spatial information relies on egocentric (body-based) and allocentric (environment-based) frames of reference. Research showed that spatial memory deteriorates as Alzheimer's disease (AD) progresses and that allocentric spatial memory is among the earliest impaired areas. Most studies have been conducted in static situations despite the dynamic nature of real-world spatial processing.
View Article and Find Full Text PDFBiomimetics (Basel)
December 2024
Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, Changchun 130022, China.
Slender tubes are in high demand owing to their lightweight and outstanding energy absorption. However, conventional slender tubes are prone to catastrophic failures such as Euler's buckling under axial load. Interestingly, growing bamboos overcome this similar dilemma via a unique tapered intine in the internodes, which endows them with excellent energy absorption.
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