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Contrastive learning with transformer for adverse endpoint prediction in patients on DAPT post-coronary stent implantation.
Front Cardiovasc Med
January 2025
Department of Artificial Intelligence and Informatics, Mayo Clinic, Jacksonville, FL, United States.
Background: Effective management of dual antiplatelet therapy (DAPT) following drug-eluting stent (DES) implantation is crucial for preventing adverse events. Traditional prognostic tools, such as rule-based methods or Cox regression, despite their widespread use and ease, tend to yield moderate predictive accuracy within predetermined timeframes. This study introduces a new contrastive learning-based approach to enhance prediction efficacy over multiple time intervals.
View Article and Find Full Text PDFGenomic Drivers of Coronary Artery Disease and Risk of Future Outcomes After Coronary Angiography.
JAMA Netw Open
January 2025
Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Importance: Disease characteristics of genetically mediated coronary artery disease (CAD) on coronary angiography and the association of genomic risk with outcomes after coronary angiography are not well understood.
Objective: To assess the angiographic characteristics and risk of post-coronary angiography outcomes of patients with genomic drivers of CAD: familial hypercholesterolemia (FH), high polygenic risk score (PRS), and clonal hematopoiesis of indeterminate potential (CHIP).
Design, Setting, And Participants: A retrospective cohort study of 3518 Mass General Brigham Biobank participants with genomic information who underwent coronary angiography was conducted between July 18, 2000, and August 1, 2023.
Fast-Track Aspirin Odyssey: ICU Chronicles.
Cureus
September 2024
Internal Medicine, Monmouth Medical Center, Rutgers University, Long Branch, USA.
Aspirin is used in patients with coronary artery disease essential in both acute and chronic phases of treatment, especially post-catheterization and post-coronary artery stent placement. Some patients have sensitivity to aspirin. Hypersensitivity reaction symptoms include itchy and watery eyes, itchy rash, worsening asthma, wheezing to fatal angioedema, and anaphylaxis.
View Article and Find Full Text PDFInfected stent graft and severe aortitis after transcaval glue embolization of type II endoleak: a case report.
AME Case Rep
May 2024
Department of Radiology, Mayo Clinic Health System, Eau Claire, WI, USA.
Article Synopsis
- - Type II endoleaks are common after aortic stent graft procedures, often requiring treatment such as transarterial or trans-caval embolization, but complications like infections can arise, as highlighted in a unique case study.
- - A 71-year-old male developed an infected Gore Excluder stent graft following trans-caval embolization for a type II endoleak, which was complicated by rapid sac enlargement and difficult-to-diagnose inflammation.
- - After two weeks of pre-surgery optimization due to the patient's high surgical risk, the infected graft was surgically removed, revealing adhesion to nearby intestines, and the patient recovered with only minor postoperative issues.
Drug-eluting balloon to treat immediate post-coronary artery bypass grafting ST-elevation myocardial infarction: a case report.
Eur Heart J Case Rep
June 2024
Department of Cardiology and Cardiac Surgery, Hull University Teaching Hospitals, Cottingham, UK.
Background: Coronary artery bypass graft (CABG) surgery represents a major cardiovascular operation and may be associated with post-operative ST-elevation myocardial infarction (STEMI) due to graft failure. This is challenging to diagnose and treat as the implanted grafts may be prone to complications when treated percutaneously with drug-eluting stents.
Case Summary: A man in his 60 s underwent CABG and developed new persistent ST elevations of 2 mm in anterior leads with no significant chest pain, although, administered with intravenous opiates post-operatively.
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