Aim: To evaluate the influence of smoking on the outcome of COH and IUI in subfertile couples.
Patients And Methods: We reviewed the medical files of all consecutive women, age
Results: A total of 2,318 cases were evaluated: 1,803 in nonsmoking patients (n = 679) and 515 in smokers (n = 206). The smokers used significantly more gonadotropin ampoules and gained a thinner endometrium on the day of hCG administration than the nonsmokers (p < 0.016 for both). There were no between-groups differences in patient age, duration of gonadotropin stimulation, number of follicle >14 mm in diameter, or E2 levels on the day of hCG administration.
Conclusion: Smokers undergoing COH with IUI required a significantly higher gonadotropin dosage than nonsmokers in order to achieved a comparable pregnancy rate.
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| http://dx.doi.org/10.1007/s10815-009-9330-x | DOI Listing |
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