We extend the study of weak local conditional independence (WCLI) based on a measurability condition made by (Commenges and Gégout-Petit J R Stat Soc B 71:1-18) to a larger class of processes that we call D'. We also give a definition related to the same concept based on certain likelihood processes, using the Girsanov theorem. Under certain conditions, the two definitions coincide on D'. These results may be used in causal models in that we define what may be the largest class of processes in which influences of one component of a stochastic process on another can be described without ambiguity. From WCLI we can construct a concept of strong local conditional independence (SCLI). When WCLI does not hold, there is a direct influence while when SCLI does not hold there is direct or indirect influence. We investigate whether WCLI and SCLI can be defined via conventional independence conditions and find that this is the case for the latter but not for the former. Finally we recall that causal interpretation does not follow from mere mathematical definitions, but requires working with a good system and with the true probability.
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http://dx.doi.org/10.1007/s10985-009-9131-7 | DOI Listing |
Sci Rep
January 2025
Exploration and Development Research Institute, PetroChina Tarim Oilfield Company, Korla, 841000, China.
The reservoir in focus has braided river delta front deposition, with multiple periods of submerged distributary channels within the reservoir. It also displays frequent cutting and stacking with local-connecting characteristics. Forecasting the sand distribution characteristics between wells in this type of reservoir brings a significant challenge for modeling.
View Article and Find Full Text PDFCell Death Discov
January 2025
Laboratory Animal Resource Center in Trans-Border Medical Research Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
A limited number of female germ cells support reproduction in many mammals. The follicle, composed of oocytes and supporting granulosa cells, forms the basis of oogenesis. Crosstalk between oocytes and granulosa cells is essential for the formation, dormancy, re-awakening, and maturation of oocytes.
View Article and Find Full Text PDFCommun Chem
January 2025
Institute of Biochemistry, University of Münster, Münster, Germany.
Translation of mRNA into protein is a fundamental process and tightly controlled during development. Several mechanisms acting on the mRNA level regulate when and where an mRNA is expressed. To explore the effects of conditional and transient gene expression in a developing organism, it is vital to experimentally enable abrogation and restoration of translation.
View Article and Find Full Text PDFCell Commun Signal
January 2025
Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Purpose: Cardiomyocyte death is a major cytopathologic response in acute myocardial infarction (AMI) and involves complex inflammatory interactions. Although existing reports indicating that mixed lineage kinase domain-like protein (MLKL) is involved in macrophage necroptosis and inflammasome activation, the downstream mechanism of MLKL in necroptosis remain poorly characterized in AMI.
Methods: MLKL knockout mice (MLKL), RIPK3 knockout mice (RIPK3), and macrophage-specific MLKL conditional knockout mice (MLKL) were established.
J Infect
January 2025
School of Veterinary Medicine, University of Surrey, Daphne Jackson Rd, Guildford GU2 7AL, United Kingdom; The Surrey Institute for People-Centred Artificial Intelligence, Stag Hill University Campus, Guildford GU2 7XH, United Kingdom; Institute for Sustainability, University of Surrey, Guildford, United Kingdom; University of Exeter, Exeter, United Kingdom.
Objectives: This study aimed to improve the understanding of seasonal incidence pattern observed in salmonellosis by identifying the most influential weather factors, characterizing the nature of this association, and assessing whether it is geographically restricted or generalizable to other locations.
Methods: A novel statistical model was employed to estimate the incidence of salmonellosis conditional to various combinations of three simultaneous weather factors from 14 available. The analysis utilised daily salmonellosis cases reported from 2000 to 2016 along with detailed spatial and temporal weather data from England and Wales, and the Netherlands.
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