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Practical disk diffusion test for detecting group B streptococcus with reduced penicillin susceptibility. | LitMetric

AI Article Synopsis

  • Recent findings show that group B streptococcus (GBS) can have reduced susceptibility to penicillin, known as PRGBS.
  • Researchers created a new, effective screening method for PRGBS in clinical labs using specific antibiotic disks (ceftibuten, oxacillin, and ceftizoxime).
  • This method aims to improve detection of PRGBS and enhance treatment decisions in clinical microbiology.

Article Abstract

Although group B streptococcus (GBS) has been considered to be uniformly susceptible to beta-lactams, the presence of GBS with reduced penicillin susceptibility (PRGBS) was recently confirmed genetically. We developed a feasible and reliable method for screening PRGBS in clinical microbiology laboratories using a combination of ceftibuten, oxacillin, and ceftizoxime disks.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786660PMC
http://dx.doi.org/10.1128/JCM.02063-08DOI Listing

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