The article deals with a review of the present-day literature data regarding administration of lipid-decreasing agents--statins in clinical practice of cardiologists and heart surgeons. In the context of the constantly accumulating evidence-based findings concerning efficacy of administration of statins in patients suffering from cardiovascular diseases, the authors describe the importance of therapy with statins in order to prevent complications after atherothrombosis.

Download full-text PDF

Source

Publication Analysis

Top Keywords

[statins practice
4
practice vascular
4
vascular surgeon
4
surgeon cardiologist]
4
cardiologist] article
4
article deals
4
deals review
4
review present-day
4
present-day literature
4
literature data
4

Similar Publications

Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) play a vital role in managing and preventing cardiovascular disease, particularly in elderly populations who face elevated risks for atherosclerosis and related conditions. This review delves into the mechanisms of statin action, emphasizing their impact on low-density lipoprotein cholesterol levels, anti-inflammatory properties, and potential genetic factors influencing efficacy and drug tolerability. Consideration is given to statin intolerance and management strategies, drug interactions, and guidelines for primary and secondary prevention of cardiovascular events.

View Article and Find Full Text PDF

Statin therapy in primary and secondary cardiovascular disease prevention.

Curr Atheroscler Rep

December 2024

Hellenic Endocrine Network, 6, Ermou St, Athens, Greece.

Purpose Of Review: Atherosclerotic cardiovascular disease (ASCVD) is one of the most common causes of death globally and the leading one in the US. Elevated low-density lipoprotein (LDL) cholesterol is one of the main modifiable disease risk factors and statin therapies have been extensively studied in that regard. The present work presents the clinical trials derived evidence supporting the use of statins in primary and secondary cardiovascular disease prevention.

View Article and Find Full Text PDF

Deprescribing Cardiovascular Medications in Older Adults Living with Frailty.

CJC Open

December 2024

Division of Cardiology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Certain medications have shown significant effectiveness in reducing the incidence of cardiovascular events and mortality, leading them to be among those that are prescribed most commonly for Canadian seniors. However, polypharmacy, which disproportionately affects older adults, is particularly concerning for frail individuals who are at higher risk for adverse medication-related events. The deprescribing process is the discontinuation, either immediate or gradual, of inappropriate medications, to address polypharmacy and improve outcomes.

View Article and Find Full Text PDF

Background: Practice guidelines recommend patient management based on scientific evidence. Quality indicators gauge adherence to such recommendations and assess health care quality. They are usually defined as adverse event rates, which may not fully capture guideline adherence over time.

View Article and Find Full Text PDF

This study evaluated the management of dyslipidemia in Turkey with the goal of understanding current diagnosis and treatment patterns, as well as identifying unmet needs in achieving effective low-density lipoprotein cholesterol (LDL-C) targets. Using a Delphi panel consisting of nine expert cardiologists, the study reveals key gaps in dyslipidemia management, particularly in the underutilization of combination therapies, such as statins and PCSK9 inhibitors, which are crucial for achieving LDL-C targets in high-risk patients. The findings indicate that while many patients with very high cardiovascular risk are diagnosed, a significant proportion do not receive optimal treatment to reach LDL-C levels recommended by European guidelines.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!