Calcifying fibrous pseudotumor in association with hyaline vascular type Castleman's disease.

Indian J Pathol Microbiol

Department of Pathology and Microbiology, Aga Khan University Karachi, Pakistan.

Published: December 2009

Calcifying fibrous pseudotumor is a recently described rare entity. It is considered as sclerosing end stage of inflammatory myofibroblastic tumor. An association with hyaline vascular type Castleman's disease has also been described. We report a case of a 13-year-old boy who presented with pain in epigastrium. Computed tomography scan of abdomen revealed a circumscribed mass arising from the gastric wall along the greater curvature. Histology revealed a tumor composed of spindle cells present within the dense hyalinized collagenous tissue. Lymphoplasmacytic infiltrate was seen along with lymphoid follicles, dystrophic and ossifying calcification. Tumor cells were focally positive for alpha smooth muscle actin and negative for anaplastic lymphoma kinase protein.

Download full-text PDF

Source
http://dx.doi.org/10.4103/0377-4929.56151DOI Listing

Publication Analysis

Top Keywords

calcifying fibrous
8
fibrous pseudotumor
8
association hyaline
8
hyaline vascular
8
vascular type
8
type castleman's
8
castleman's disease
8
pseudotumor association
4
disease calcifying
4
pseudotumor described
4

Similar Publications

Predicting Plaque Regression Based on Plaque Characteristics Identified by Optical Coherence Tomography: A Retrospective Study.

Photodiagnosis Photodyn Ther

January 2025

Department of Cardiology, Shanghai East Hospital of Clinical Medical College, Nanjing Medical University, Nanjing 211166, China; Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China. Electronic address:

Background: Atherosclerosis is a lipid-driven, systemic immune-inflammatory disease characterized by the accumulation of plaque within the arterial walls. Plaque regression can occur following appropriate treatment interventions. Optical coherence tomography (OCT), a high-resolution imaging modality, is frequently employed to assess plaque morphology.

View Article and Find Full Text PDF

Carotid plaques-the buildup of cholesterol, calcium, cellular debris, and fibrous tissues in carotid arteries-can rupture, release microemboli into the cerebral vasculature and cause strokes. The likelihood of a plaque rupturing is thought to be associated with its composition (i.e.

View Article and Find Full Text PDF

Background: Preliminary research indicates that higher iron levels are associated with worse outcomes in patients with coronary artery disease.

Aims: The study aimed to investigate the relationship between iron levels and the type and composition of coronary plaques.

Methods: In patients with ≥1 coronary stenosis ≥50% on computed tomography angiography, iron levels, presence of high-risk plaque features, such as low-attenuation plaque (LAP), napkin-ring sign, positive remodeling, and spotty calcium, as well as type and plaque composition (calcified/fibrous/fibro-fatty/necrotic core) were evaluated.

View Article and Find Full Text PDF

Background: Stroke is a leading cause of death and disability worldwide, affecting millions annually. Accurate etiological diagnosis is critical for the effective treatment and prevention of recurrent strokes. Traditional luminal imaging techniques like computed tomography (CT) and magnetic resonance angiography (MRA) provide limited information, focusing solely on vessel lumen characteristics.

View Article and Find Full Text PDF

Ultrasound Strain Imaging for Characterizing Atherosclerotic Plaque in the Carotid Arteries of Asymptomatic Subjects.

Ultrasound Med Biol

February 2025

Department of Medical Imaging, Medical UltraSound Imaging Center, Radboud University Medical Center, Nijmegen, The Netherlands; Physics of Fluids Group, University of Twente, Meander (27), Enschede, The Netherlands. Electronic address:

Objective: The rupture of vulnerable plaques in the carotid artery is a leading cause of strokes. While magnetic resonance imaging (MRI) is the standard for quantifying plaque composition, its high costs and lengthy procedure times limit large-scale use. Compound ultrasound strain imaging (CUSI) ultrasound offers a non-invasively alternative by assessing tissue deformation/strain within the arterial wall.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!