Selective inference in complex research.

Philos Trans A Math Phys Eng Sci

Department of Statistics and Operations Research, Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel.

Published: November 2009

We explain the problem of selective inference in complex research using a recently published study: a replicability study of the associations in order to reveal and establish risk loci for type 2 diabetes. The false discovery rate approach to such problems will be reviewed, and we further address two problems: (i) setting confidence intervals on the size of the risk at the selected locations and (ii) selecting the replicable results.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263782PMC
http://dx.doi.org/10.1098/rsta.2009.0127DOI Listing

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