Short stereoselective syntheses of various cyclitols, including the derivatives of conduritol B, conduritol F, myo-inositol and chiro-inositol, have been accomplished. The key steps in the syntheses are a ring-closing metathesis process and a diastereodivergent organometallic addition to a D-xylose-derived alde-hyde.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711561 | PMC |
http://dx.doi.org/10.1055/s-2008-1067260 | DOI Listing |
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