Unlabelled: Laffont I, Biard N, Chalubert G, Delahoche L, Marhic B, Boyer FC, Leroux C. Evaluation of a graphic interface to control a robotic grasping arm: a multicenter study.
Objective: Grasping robots are still difficult to use for persons with disabilities because of inadequate human-machine interfaces (HMIs). Our purpose was to evaluate the efficacy of a graphic interface enhanced by a panoramic camera to detect out-of-view objects and control a commercialized robotic grasping arm.
Design: Multicenter, open-label trial.
Setting: Four French departments of physical and rehabilitation medicine.
Participants: Control subjects (N=24; mean age, 33y) and 20 severely impaired patients (mean age, 44y; 5 with muscular dystrophies, 13 with traumatic tetraplegia, and 2 others) completed the study. None of these patients was able to grasp a 50-cL bottle without the robot.
Interventions: Participants were asked to grasp 6 objects scattered around their wheelchair using the robotic arm. They were able to select the desired object through the graphic interface available on their computer screen.
Main Outcome Measures: Global success rate, time needed to select the object on the screen of the computer, number of clicks on the HMI, and satisfaction among users.
Results: We found a significantly lower success rate in patients (81.1% vs 88.7%; chi(2)P=.017). The duration of the task was significantly higher in patients (71.6s vs 39.1s; P<.001). We set a cut-off for the maximum duration at 79 seconds, representing twice the amount of time needed by the control subjects to complete the task. In these conditions, the success rate for the impaired participants was 65% versus 85.4% for control subjects. The mean number of clicks necessary to select the object with the HMI was very close in both groups: patients used (mean +/- SD) 7.99+/-6.07 clicks, whereas controls used 7.04+/-2.87 clicks. Considering the severity of patients' impairment, all these differences were considered tiny. Furthermore, a high satisfaction rate was reported for this population concerning the use of the graphic interface.
Conclusions: The graphic interface is of interest in controlling robotic arms for disabled people, with numerous potential applications in daily life.
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http://dx.doi.org/10.1016/j.apmr.2009.05.009 | DOI Listing |
J Chem Inf Model
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Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
The screening of chemical libraries is an essential starting point in the drug discovery process. While some researchers desire a more thorough screening of drug targets against a narrower scope of molecules, it is not uncommon for diverse screening sets to be favored during the early stages of drug discovery. However, a cost burden is associated with the screening of molecules, with potential drawbacks if particular areas of chemical space are needlessly overrepresented.
View Article and Find Full Text PDFJ Proteome Res
January 2025
Applied Bioinformatics, Department of Computer Science, University of Tübingen, Tübingen 72074, Germany.
Liquid chromatography-mass spectrometry (LC-MS) is an indispensable analytical technique in proteomics, metabolomics, and other life sciences. While OpenMS provides advanced open-source software for MS data analysis, its complexity can be challenging for nonexperts. To address this, we have developed OpenMS WebApps, a framework for creating user-friendly MS web applications based on the Streamlit Python package.
View Article and Find Full Text PDFSci Rep
January 2025
Instituto Politécnico Nacional, Centro de Desarrollo Aeroespacial, 06610, Mexico City, Mexico.
This work presents the design and validation of a thermal subsystem for a 1U CubeSat-type nanosatellite. The design encompasses two stages: regulating the satellite's temperature range through implementing passive control based on multilayer coatings and an electronic board capable of measuring the internal surface temperature of each of the satellite's six faces. Validation is conducted through tests performed in a theoretical thermo vacuum chamber that provides a controlled environment, simulating the thermal conditions to which the satellite will be exposed once in orbit.
View Article and Find Full Text PDFPLoS Biol
January 2025
School of Biosciences and Bateson Centre, University of Sheffield, Western Bank, Sheffield, United Kingdom.
Heart development involves the complex structural remodelling of a linear heart tube into an asymmetrically looped and ballooned organ. Previous studies have associated regional expansion of extracellular matrix (ECM) space with tissue morphogenesis during development. We have developed morphoHeart, a 3D tissue segmentation and morphometry software with a user-friendly graphical interface (GUI) that delivers the first integrated 3D visualisation and multiparametric analysis of both heart and ECM morphology in live embryos.
View Article and Find Full Text PDFNano Lett
January 2025
Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Tomtebodavägen 23, 17165 Solna, Sweden.
Single particle profiling (SPP) is a unique methodology to study nanoscale bioparticles such as liposomes, lipid nanoparticles, extracellular vesicles, and lipoproteins in a single particle and high throughput manner. The initial version requires the single photon counting modules for data acquisition, which limits its adoptability. Here, we present imaging-based SPP (iSPP) that can be performed by imaging a spot over time in the common imaging mode with confocal detectors.
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