In the present paper, the influence of the pure spectrum contained in the mixed spectrum was centralized at the origin, and in this way, the influence of the pure spectrum in the result curve reached the maximum value. This process is called the self intensification of the pure spectrum. Farther, considering that the center of the Gaussian function contained in the impure spectrum is much different from that of the pure spectrum, it can be accepted that the influence of the impure spectrum at the origin is approximately the minimum. So the origin was chosen as the analysis point when the authors perform the quantitative analysis according to the spectrum. Therefore we can reduce the subjectivity in choosing the analysis point. In addition, the wavelet coefficients of the result curve at the origin were used for the quantitative analysis. According to the simulated experiment, it was found that the final result is independent of the Gaussian white noise contained in the actual spectrum. Finally, the analytic result of the new method was compared with that of the method reported in the literature, which proved that the new method is much better in terms of the analytic error.
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Anal Biochem
January 2025
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Nahda University (NUB), 62511 Beni-Suef, Egypt.
The 2019 coronavirus outbreak has prompted scientists to investigate pharmaceuticals to prevent the spread of the disease. Favipiravir (FAV) has received Food and Drug Administration FDA approval for the treatment of various viral infections with notable efficacy in clinical trials for COVID-19. Nitazoxanide (NTZ) is a broad-spectrum antiparasitic and antiviral agent used for the treatment of parasitic illnesses.
View Article and Find Full Text PDFCureus
December 2024
Department of Dermatology, Venereology and Leprosy, Great Eastern Medical School & Hospital, Srikakulam, IND.
Leprosy, or Hansen's disease, is an ancient infectious disease characterized by varied clinical presentations influenced by the host's immune response. This study aimed to explore the atypical manifestations of Hansen's disease in a cohort of 15 biopsy-confirmed patients admitted to the Department of Dermatology, Venereology & Leprosy at a tertiary care center in Andhra Pradesh, India. There were 14 male patients and one female patient, with a mean age of 42.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai 608 502, Tamil Nadu, India.
A bio-fabrication approach is a novel way to develop chitosan-stabilized magnesium oxide nanomaterials (cMgO-NMs). The process involves utilizing polymeric chitosan as the reducing and stabilizing agent. The characteristics of the developed cMgO-NMs were determined using various spectroscopical techniques.
View Article and Find Full Text PDFPLoS One
January 2025
College of Physics and Electronic Engineering, Hainan Normal University, HaiKou, China.
We have successfully prepared a significant number of nanowires from non-toxic silicon sources. Compared to the SiO silicon source used in most other articles, our preparation method is much safer. It provides a simple and harmless new preparation method for the preparation of silicon nanowires.
View Article and Find Full Text PDFJ Neurol
January 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China.
Background And Objective: Neuronal intranuclear inclusion disease (NIID) is a multifaceted disorder impacting both the central and peripheral nervous systems. This study aims to investigate the clinical and electrophysiological characteristics of peripheral neuropathy in patients with NIID.
Methods: In this cross-sectional study, patients diagnosed with NIID were prospectively recruited from multiple centers across China between October 2017 and May 2024.
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