Pre-dialysis insulin: a new concept to treat an old problem.

Br J Nurs

Richard Brifht Renal Unit, North Bistol NHS Trust, Southmead Hospital, Bristol.

Published: November 2009

Diabetes and chronic kidney disease are two disease processes that remain with the patient from diagnosis to the end of their lives. The field of diabetes and renal failure is a complex area, merging together these two chronic diseases, each a speciality in its own right. Patients with diabetes need to start dialysis much earlier than those without diabetes due to the cumulative effect of proteinuria and its associated symptoms.The single largest cause of end-stage renal disease continues to be diabetes and within the field of renal nursing, we have seen an increase in the number of patients with diabetes entering the dialysis programme in recent years. The author's personal experience is that once on haemodialysis, we have seen traditional treatments fail to meet the individual needs of this cohort and have devised a programme of insulin delivery that appears to fill this gap.

Download full-text PDF

Source
http://dx.doi.org/10.12968/bjon.2009.18.17.44157DOI Listing

Publication Analysis

Top Keywords

patients diabetes
8
diabetes
6
pre-dialysis insulin
4
insulin concept
4
concept treat
4
treat problem
4
problem diabetes
4
diabetes chronic
4
chronic kidney
4
kidney disease
4

Similar Publications

Obesity significantly influences drug pharmacokinetics (PK), which challenges optimal dosing. This study examines the effects of diet-and-exercise-induced weight loss on key drug-metabolizing enzymes and gastric emptying in patients with obesity, who frequently require medications for comorbidities. Participants followed a structured weight management program promoting weight loss over 3-6 months and were not concomitantly on potential CYP inducers or inhibitors.

View Article and Find Full Text PDF

Aims: Evaluate glycated haemoglobin (HbA1c) and weight changes after 6 months of once-weekly (QW) injectable glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy in UK primary care.

Materials And Methods: Retrospective, non-interventional study, using the Clinical Practice Research Datalink Aurum primary care database, identified adults with type 2 diabetes (T2D) newly initiating a QW injectable GLP-1 RA between January 2020 and November 2021. Dual primary outcomes were proportion of patients with (1) HbA1c < 7% (<53 mmol/mol) and (2) weight loss categories (from 0% to 15+%) after 6 months of continuous GLP-1 RA therapy.

View Article and Find Full Text PDF

CAMKIIδ Reinforces Lipid Metabolism and Promotes the Development of B Cell Lymphoma.

Adv Sci (Weinh)

January 2025

Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, China.

The most prevalent types of lymphomas are B cell lymphomas (BCL). Newer therapies for BCL have improved the prognosis for many patients. However, approximately 30% with aggressive BCL either remain refractory or ultimately relapse.

View Article and Find Full Text PDF

Background: Despite fractional flow reserve (FFR)-guided deferral of revascularization, recurrent events in patients with diabetes or after myocardial infarction remain common. This study aimed to assess the association between FFR-negative but high-risk nonculprit lesions and clinical outcomes.

Methods: This is a patient-level pooled analysis of the prospective natural-history COMBINE (OCT-FFR) study (Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients) and PECTUS-obs study (Identification of Risk Factors for Acute Coronary Events by OCT After STEMI and NSTEMI Patients With Residual Non- Flow Limiting Lesions).

View Article and Find Full Text PDF

Diabetes mellitus (DM) is recognized and classified as a group of conditions marked by persistent high blood glucose levels. It is also an inflammatory condition that may influence concurrent disease states, including Coronavirus Disease 2019 (COVID-19). Currently, no effective drug has been found to treat COVID-19, especially in DM patients.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!