The aim of the present study was to examine executive dysfunctioning and decreased processing speed as potential mediators of age-related differences in episodic memory. We compared the performances of young and elderly adults in a free-recall task. Participants were also given tests to measure executive functions and perceptual processing speed and a coding task (the Digit Symbol Substitution Test, DSST). More precisely, we tested the hypothesis that executive functions would mediate the age-related differences observed in the free-recall task better than perceptual speed. We also tested the assumption that a coding task, assumed to involve both executive processes and perceptual speed, would be the best mediator of age-related differences in memory. Findings first confirmed that the DSST combines executive processes and perceptual speed. Secondly, they showed that executive functions are a significant mediator of age-related differences in memory, and that DSST performance is the best predictor.
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http://dx.doi.org/10.1016/j.bandc.2009.08.007 | DOI Listing |
Int J Legal Med
January 2025
University Department of Forensic Sciences, University of Split, R. Boškovića 33, Split, 21000, Croatia.
This study aimed to test age-related changes in sternal fusion and sternal-rib cartilage ossification on multi-slice computed tomography (MSCT) images of the Croatian population. The additional aim was to develop models to estimate age and provide an interface for the model's application and validation. This retrospective study was conducted on 144 MSCT images of the sternal region, and the developed models were tested on 36 MSCT images.
View Article and Find Full Text PDFBrain Struct Funct
January 2025
Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.
Front Behav Neurosci
December 2024
Basque Center on Cognition, Brain and Language (BCBL), Donostia-San Sebastián, Spain.
Extensive behavioral research on adults has shown that retrieval practice is highly beneficial for long-term memory retention. However, limited evidence exists on the developmental course of this benefit. Here, we present data from a behavioral study involving 7-14-year-old children who had to encode a total of 60 weakly semantically related cue-target word pairs using either repeated retrieval or repeated study encoding strategies.
View Article and Find Full Text PDFFront Aging
December 2024
Department of Molecular Medicine, Princess Al Jawhara Center, College of Medicine and Health Sciences, Arabian Gulf University, Manama, Bahrain.
Biological age is a concept that reflects the physiological state of an individual rather than the chronological time since birth. It can help assess the risk of age-related diseases and mortality and the effects of interventions to slow down or reverse aging. However, there is no consensus on measuring biological age best, and different methods may yield different results.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, 141700 Dolgoprudny, Russian Federation; Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, Dubna, 141980, Russian Federation. Electronic address:
Ferritin-based hybrids are large 24-subunit macromolecules of megadalton scale have prospective applications ranging from drug delivery to recombinant vaccines, however, their rational design is challenging. Here, we architectured hybrids based on ferritin subunits from Helicobacter pylori and ones fused with a homolog of the Small Ubiquitin-like Modifier protein. We firstly revealed the stochastic nature of bacterial ferritin-based hybrids self-assembly by observing a sequential range of stoichiometries at totally different sample preparation procedures: coexpression in Escherichia coli cells and pH-dependent dis/reassembly.
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