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Article Abstract
Two novel SF5 analogs of the antimalarial agent mefloquine were synthesized in 5 steps and 10-23% overall yields and found to have improved activity and selectivity against malaria parasites. This work also represents the first report of SF5-substituted quinolines.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929370 | PMC |
| http://dx.doi.org/10.1039/b911483a | DOI Listing |
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