The existence of two or more diagnoses (psychiatric, or a combination with somatic) in one person leads to a dilemma when choosing psychopharmacs for the treatment of the patient. There are no acceptable and comprehensive guidelines or algorithms for the treatment of innumerable possible combinations of psychiatric and somatic disorders. A strategy for treatment of such conditions is needed.
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AIDS Res Treat
January 2025
Department of Health Promotion and Behavioral Sciences, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Depression in women living with HIV (WLWHIV), is one of the most common public health concerns worldwide. Depression has a negative impact on antiretroviral therapy (ART) adherence, quality of life, poor HIV treatment outcomes, and mortality. However, there is a paucity of evidence in low-income countries such as Ethiopia in WLWHIV.
View Article and Find Full Text PDFWorld J Psychiatry
January 2025
The Second Clinical Medical College, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
A recent study by Wang , published in the , provided preventative and therapeutic strategies for the comorbidity of obesity and depression. The gutbrain axis, which acts as a two-way communication system between the gastrointestinal tract and the central nervous system, plays a pivotal role in the pathogenesis of these conditions. Evidence suggests that metabolic byproducts, such as short-chain fatty acids, lipopolysaccharide and bile acids, which are generated by the gut microbiota, along with neurotransmitters and inflammatory mediators within the gut-brain axis, modulate the host's metabolic processes, neuronal regulation, and immune responses through diverse mechanisms.
View Article and Find Full Text PDFWorld J Psychiatry
January 2025
International Education School, China Medical University, Shenyang 110004, Liaoning Province, China.
There is growing evidence that interleukin (IL)-6 plays an important role in neurological and psychiatric disorders. This editorial comments on the study published in the recent issue of the , which employed Mendelian randomization to identify a causal relationship between IL-6 receptor blockade and decreased epilepsy incidence. The purpose of this editorial is to highlight the dual effects of IL-6 in epilepsy and its related neuropsychiatric comorbidities.
View Article and Find Full Text PDFPerspect ASHA Spec Interest Groups
December 2024
DeVault Otologic Research Laboratory, Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis.
Purpose: Cochlear implants (CIs) have improved the quality of life for many children with severe-to-profound sensorineural hearing loss. Despite the reported CI benefits of improved speech recognition, speech intelligibility, and spoken language processing, large individual differences in speech and language outcomes are still consistently reported in the literature. The enormous variability in CI outcomes has made it challenging to predict which children may be at high risk for limited benefits and how potential risk factors can be improved with interventions.
View Article and Find Full Text PDFAlpha Psychiatry
November 2024
Department of Geriatrics, Capital Medical University, Xuanwu Hospital, National Clinical Research Center for Geriatric Diseases, Beijing, China.
Objective: The objective is to investigate the situation and risk factors of depression in aged, hospitalized patients with chronic heart failure (CHF).
Methods: A total of 196 aged CHF patients admitted to Xuanwu Hospital from May 2022 to March 2024 were consecutively selected. Information such as demographics, comorbidities, old-age hospitalization assessment results, and admission test results was collected.
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