Beyond specific pathogen-free: biology and effect of common viruses in macaques.

Comp Med

California National Primate Research Center, University of California, Davis, CA, USA.

Published: February 2008

AI Article Synopsis

  • Macaque models have been instrumental in enhancing our understanding of behavior, anatomy, physiology, and various human diseases.
  • This issue of Comparative Medicine highlights specific viral agents that affect both nonhuman primates and humans, potentially complicating research efforts.
  • The articles also discuss the difficulties in cultivating macaque colonies that are genuinely free of specific pathogens and other unintended infectious agents.

Article Abstract

Macaque models have contributed to key advances in our basic knowledge of behavior, anatomy, and physiology as well as to our understanding of a wide variety of human diseases. This issue of Comparative Medicine focuses on several of the viral agents (members of Retroviridae, Herpesviridae and 2 small DNA viruses) that can infect both nonhuman primates and humans as well as confound research studies. Featured articles also address the challenges of developing colonies of macaques and other nonhuman primates that are truly specific pathogen-free for these and other adventitious infectious agents.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703162PMC

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