Setting: External quality assessment (EQA) of Mycobacterium tuberculosis drug susceptibility testing (DST) in bacteriological tuberculosis (TB) laboratories in the Russian Federation.
Objective: To improve the EQA of DST of first-line anti-tuberculosis drugs using proficiency testing in the Russian Federation.
Method: Three rounds of DST proficiency testing using Mycobacterium tuberculosis isolates provided by the Swedish Institute for Infectious Disease Control, a World Health Organization Supranational Reference Laboratory (SRL). In total, 42 TB laboratories in the Russian civilian and prison sectors participated in at least one round of proficiency testing, and 17 laboratories participated in all three rounds.
Results: Ninety-seven per cent (87/89) of reports were received for the three rounds: 67% of laboratories in the first round and 86% of laboratories in the second round demonstrated >or=95% accuracy for isoniazid, and respectively 72% and 80% of laboratories in the first and second rounds reported >or=95% accuracy for rifampicin.
Conclusion: Coordination with the SRL network resulted in the introduction of 90 well-characterised strains for EQA in the Russian Federation. Successive rounds of DST proficiency testing have helped to identify highly proficient laboratories that will be used as expert laboratories for proficiency testing in the future.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Evaluating the accuracy of multiple rapid diagnostic tests for HIV detection in serum samples analysed during point-of-care proficiency testing assessments.
Diagn Microbiol Infect Dis
January 2025
Centre for HIV & Sexually Transmitted Infections, National Institute for Communicable Diseases, Division of National Health Laboratory Service, Johannesburg, South Africa.
Background: HIV rapid diagnostic tests are crucial for timely diagnosis, especially in resource-limited settings. The World Health Organization recommends sensitivity ≥99 % and specificity ≥98 %. This study assessed RDT performance across South Africa's provinces using a proficiency testing program.
View Article and Find Full Text PDFEnhancing lane detection in autonomous vehicles with multi-armed bandit ensemble learning.
Sci Rep
January 2025
School of Computer Science Engineering and Information Systems, Vellore Institute of Technology, Vellore, India.
This study introduces a novel ensemble learning technique namely Multi-Armed Bandit Ensemble (MAB-Ensemble), designed for lane detection in road images intended for autonomous vehicles. The foundation of the proposed MAB-Ensemble technique is inspired in terms of Multi-Armed bandit optimization to facilitate efficient model selection for lane segmentation. The benchmarking dataset namely TuSimple is used for training, validating and testing the proposed and existing lane detection techniques.
View Article and Find Full Text PDFExploring Literacy and Knowledge Gaps and Disparities in Genetics and Oncogenomics Among Cancer Patients and the General Population: A Scoping Review.
Healthcare (Basel)
January 2025
Centre for Research and Technology Hellas, Institute of Applied Biosciences, 57001 Thessaloniki, Greece.
Background: Genetic and genomic literacy is pivotal in empowering cancer patients and citizens to navigate the complexities of omics sciences, resolve misconceptions surrounding clinical research and genetic/genomic testing, and make informed decisions about their health. In a fast-evolving scenario where routine testing has become widespread in healthcare, this scoping review sought to pinpoint existing gaps in literacy and understanding among cancer patients and the general public regarding genetics and genomics.
Methods: Adhering to the PRISMA framework, the review included 43 studies published between January 2018 and June 2024, which evaluated the understanding of genetics and genomics among cancer patients, caregivers, and citizens.
Leveraging human centered design to enhance clinician communication during pregnancy care: Overcoming language barriers with Spanish-speaking patients.
PEC Innov
June 2025
Ariadne Labs at Brigham and Women's Hospital and Harvard T.H. Chan School of Public Health, 401 Park Dr, 3rd Floor, Boston, MA 02215, USA.
Background: Engaging patients in quality improvement and innovation projects is increasingly important, yet challenges persist with involving patients who speak languages other than English. This article presents design activities our team used to engage Spanish-speaking patients and cultural brokers.
Objective: To develop a clinician communication tool to enhance patient trust in pregnancy care clinicians, especially among minoritized populations who face language and cultural barriers, using human-centered design (HCD).
Ten years of the immunogenetics laboratory performance assessment programme and its impact on the donor and transplant network.
Biomedica
December 2024
Grupo Red de Donación y Trasplantes, Instituto Nacional de Salud, Bogotá, D. C., Colombia.
Introduction. The use of immunological tests before solid organ transplantation is essential to reduce the risk of rejection and post-transplant complications. Therefore, quality control systems in laboratories performing them are necessary for clinical practice.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!