The ion and fluid reabsorption during perfusion of inter-tubular capillaries with different subtypes of beta-adrenergic agonists was studied in the newt distal tubule using the micropuncture technique and X-ray microanalysis. Isoproterenol (10(-5) M) did not affect the ion and water transport. Stimulation of beta 1-adrenergic receptor with isoproterenol and beta 2-adrenergic antagonist ICI 118.551 inhibited the fractional reabsorption of sodium, chloride and magnesium, the fluid reabsorption being changed insignificantly. Stimulation of beta 2-adrenergic receptor with ventolin increased the fractional calcium reabsorption. The transport of water and other ions did not change.

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