Objective: To examine the effects of solvent exposure on hearing function, through an audiological test battery, in a population not occupationally exposed to high levels of noise.
Methods: One hundred ten workers from a coating factory were studied. Jobs at the factory were divided into three different levels of solvent exposure. Hearing status was assessed with a test battery including pure-tone hearing thresholds (0.5-8 kHz), high-frequency hearing thresholds (12 and 16 kHz), and dichotic listening measured through dichotic digits test. Multiple linear regression models were created to explore possible association between solvent exposure and each of the hearing outcomes.
Results: Significant associations between solvent exposure and the three hearing outcomes were found. Covariates such as age, gender, race, and ethnicity were also significantly associated with the studied hearing outcomes.
Conclusions: Occupational exposure to solvents may induce both peripheral and central auditory dysfunction. The dichotic digits test seems as a sensible tool to detect central auditory dysfunction associated with solvent exposure. Hearing loss prevention programs may use this tool to monitor hearing in solvent-exposed workers.
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Int J Biol Macromol
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Guangdong Key Laboratory of Intelligent Food Manufacturing, Foshan University, Foshan, Guangdong 528225, China; Department of Food Science, Foshan University, Foshan, Guangdong 528000, China. Electronic address:
The toughening coix seed oil (CSO) high internal phase Pickering emulsion (CSO-HIPES) and gel (CSO-HIPESG) comprised of carrageenan (CR)/super-deamidated-gluten (SDG) micro-particles (CR/SDG) were investigated via acid-heat induction. Results showed polysaccharide natural deep eutectic solvent (P-NADES) by citric acid-glucose-carrageenan ((CGCR), molar ratio at 1:1:0.035) was the crucial for the preparation of SDG (deamidation degree, 99.
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University of California Irvine, Irvine, CA, USA.
Background: Our goal is to identify conditions to produce structurally homogeneous and reproducible preparations of different polymorphic structures. Here we investigate the effect of several widely used methods for solubilizing Abeta on the subsequent aggregation process.
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J Mol Recognit
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Biopolymer Modeling and Protein Chemistry Laboratory, Centre for Advanced Studies in Crystallography and Biophysics, University of Madras, Chennai, India.
Bovine serum albumin (BSA) plays a crucial role as a carrier protein in plasma, binding various ligands, including drugs. Understanding the interaction between BSA and saquinavir, an antiretroviral drug, is essential for predicting its pharmacokinetics and pharmacodynamics. We employed spectroscopic approaches, including circular dichroism spectrometry and fluorescence spectroscopy, to investigate the binding of saquinavir to BSA.
View Article and Find Full Text PDFChem Asian J
January 2025
Universidad de Chile, Departamento de Quimica, Santiago, CHILE.
This study investigates the critical role of polymer matrices in optimizing luminescence and energy transfer, utilizing the commercial dyes Coumarin 6 (C6) and Rhodamine B (RhB) as a donor-acceptor pair. Solution-phase experiments revealed a dependence of energy transfer efficiency on solvent dielectric constant. Furthermore, embedding the dyes within Poly(methyl methacrylate) (PMMA) or Poly(vinyl butyral) (PVB) matrices significantly enhance energy transfer due to increased molecular proximity.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
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