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Analysis of the relevant factors for corneal graft rejection in the southern Liaoning region from 2019 to 2023.
Front Med (Lausanne)
January 2025
Dalian Medical University, Dalian, China.
Background: The study aimed to review the etiology of corneal blindness and investigate the relative risk of corneal graft rejection (CGR) in the southern Liaoning region.
Methods: The clinical records of 359 patients (394 eyes) who underwent corneal transplantation at the Department of Keratoconus of the Third People's Hospital of Dalian from January 2019 to December 2023 were retrospectively analyzed. The data included patients' age, gender, occupation, diagnosis, surgical procedure, postoperative immune rejection, and neovascularization.
Alginate-functionalized nanoceria as ion-responsive eye drop formulation to treat corneal abrasion.
Carbohydr Polym
March 2025
Department of Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, Taiwan; Department of Materials Engineering, Ming Chi University of Technology, New Taipei City 24301, Taiwan; Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 33303, Taiwan; Center for Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan. Electronic address:
In this study, we aimed to develop ion-responsive and biocompatible alginate-capped nanoceria (Ce-ALG) for β-1,3-glucan (i.e., wound healing agent) delivery and corneal abrasion (CA) treatment.
View Article and Find Full Text PDFContact Lenses in Therapeutic Care: A Comprehensive Review of Past Innovations, Present Applications, and Future Directions.
Adv Exp Med Biol
January 2025
Department of Optometry, University of Benin, Benin City, Nigeria.
Contact lenses have become integral tools in the realm of ocular therapeutics, extending beyond their primary function of refractive correction to encompass a diverse array of therapeutic applications. This review explores the evolving role of contact lenses in managing various ocular conditions, highlighting their efficacy in enhancing patient outcomes. Initially developed to correct refractive errors, contact lenses now serve as effective vehicles for delivering medications directly to the ocular surface, offering targeted treatment for conditions such as dry eye syndrome and corneal ulcers.
View Article and Find Full Text PDFIdentification of glutamine as a potential therapeutic target in dry eye disease.
Signal Transduct Target Ther
January 2025
Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing, China.
Dry eye disease (DED) is a prevalent inflammatory condition significantly impacting quality of life, yet lacks effective pharmacological therapies. Herein, we proposed a novel approach to modulate the inflammation through metabolic remodeling, thus promoting dry eye recovery. Our study demonstrated that co-treatment with mesenchymal stem cells (MSCs) and thymosin beta-4 (Tβ4) yielded the best therapeutic outcome against dry eye, surpassing monotherapy outcomes.
View Article and Find Full Text PDFEvaluation of ocular surface temperature in post-COVID-19 patients with different degrees of fever via infrared thermal imaging.
Sci Rep
January 2025
Department of Ophthalmology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
This study aimed to evaluate ocular surface temperature (OST) in post-COVID-19 patients with different degrees of fever via infrared thermal imaging. There were 16 participants (32 eyes) in the control group, 22 participants (44 eyes) in the moderate and low post-COVID-19 fever group (M & L fever group), and 18 participants (36 eyes) in the high post-COVID-19 fever group (H fever group). All participants underwent an ophthalmic slit lamp examination and ocular thermography.
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