AI Article Synopsis
- The study focuses on three patients who experienced a resurgence of obsessive-compulsive disorder (OCD) after having been symptom-free for decades, following damage to certain brain circuits.
- In addition to the return of OCD symptoms, the patients developed new symptoms such as motor and phonic tics, along with mental rituals that were linked to their cognitive and motor difficulties.
- The findings suggest a connection between brain lesions in prefronto-subcortical areas and the reactivation of OCD, indicating that these areas may play a crucial role in managing OCD symptoms.
Article Abstract
The authors describe the reactivation of obsessive-compulsive disorder (OCD) in three patients with lesions in the prefronto-subcortical circuits after decades of being asymptomatic. The patients also reported the emergence of new OCD symptoms and motor/phonic tics as well as mental rituals thematically related to the negative experience of suffering cognitive and motor deficits.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1176/jnp.2009.21.3.332 | DOI Listing |
Publication Analysis
Top Keywords
reactivation obsessive-compulsive
8
obsessive-compulsive disorder
8
late-life reactivation
4
disorder associated
4
associated lesions
4
lesions prefrontal-subcortical
4
prefrontal-subcortical circuits
4
circuits authors
4
authors describe
4
describe reactivation
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!