Aim: To evaluate the accuracy of self-reported Tanner (SRT) staging against a proxy method of physician's assessment of sexual maturation, using pubertal hormones in overweight African-American (AA) children.
Methods: Cross-sectional data from 196 children (113 girls, 83 boys) aged 9-11 years, who were 'overweight' (>85th and <95th percentile for age- and gender-matched BMI; n = 43) or 'obese' (>95th percentile; n = 153) were used. Children assessed their breast or genital and pubic hair development using standardized Tanner drawings representing different stages of sexual maturity. SRT data were compared to pubertal stage assessed by measuring fasting serum concentrations of luteinizing hormone (LH) in boys, and LH and estradiol (E2) in girls, which were used to stage children into pubertal stages 1-5.
Results: SRT stages of genital and pubic hair assessments in boys, and breast and pubic hair assessments in girls, yielded 15-20% concordance (kappa statistic = 0.02-0.12) compared to their hormone-derived pubertal stages.
Conclusions: Among overweight AA 9-11 year-old children, self-assessment of Tanner staging did not accurately assess their pubertal development when compared to a hormone-derived pubertal assessment method.
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http://dx.doi.org/10.1515/jpem.2009.22.7.609 | DOI Listing |
Am J Prev Med
January 2025
Indiana University School of Public Health-Bloomington, Bloomington, IN; Indiana University Center for Sexual Health Promotion, Bloomington, IN.
Introduction: Pubic hair removal (PHR) is a common practice, and many seek PHR from a skincare professional, or esthetician. Estheticians occupy a unique role in which they often have deep, trusting relationships and well-established rapport with their clientele, whereby they could serve as trusted providers of skin and beauty expertise, but also health promotion partners/facilitators. The purpose of this study is to explore the frequency of esthetician involvement regarding 7 potentially concerning health-related symptoms on their clients' skin and examine estheticians' comfort engaging in discussions about health, knowledge regarding these health issues, and interest in being more formally involved in their clients' health.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Baoding Hospital, Beijing Children's Hospital Affiliated with Capital Medical University, Baoding, China.
Objective: The objective of this study is to investigate the clinical presentation and underlying genetic etiology of a Chinese child diagnosed with idiopathic central precocious puberty (ICPP).
Methods: Clinical data from a pediatric patient with ICPP, including medical history, physical examination findings, laboratory results, and imaging studies, were collected and analyzed. Whole exome sequencing (WES) was performed to identify potential pathogenic genetic variants underlying the patient's ICPP.
BMJ Case Rep
January 2025
Endocrinology, Government Medical College Thiruvananthapuram, Thiruvananthapuram, Kerala, India.
We describe the case of a girl in her middle childhood who presented with signs of heterosexual precocious puberty in the form of axillary and pubic hair growth, acne and clitoromegaly. Investigations showed elevated androgens and autonomous cortisol excess, suggesting an adrenal source. CT imaging confirmed a left adrenal mass and multiple colonic polyps.
View Article and Find Full Text PDFJ Clin Res Pediatr Endocrinol
January 2025
Ankara University Faculty of Medicine, Department of Pediatric Endocrinology, Ankara, Turkey
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disease caused by the deficiency of one of the enzymes involved in cortisol synthesis. Between 90% and 99% of cases of CAH are caused by 21-hydroxylase deficiency (21-OHD) caused by mutations in . Although 21-OHD has been historically divided into classical and non-classical forms, it is now thought to show a continuous phenotype.
View Article and Find Full Text PDFJ Pediatr Endocrinol Metab
December 2024
Pediatric Endocrinology Clinic, Bilkent City Hospital, Ankara, Türkiye.
Objectives: Hypothalamic hamartoma (HH) is a rare condition that causes epilepsy and central precocious puberty (CPP) at an early age. In this report, we describe a child with CPP secondary to HH and discuss the current literature.
Case Presentation: A 26-month-old girl was brought to our hospital for evaluation of breast enlargement.
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