Breast cancer during pregnancy.

Eur J Obstet Gynecol Reprod Biol

Service de Chirurgie Gynécologique, Hôpital Jeanne de Flandre, 59037 Lille cedex, France.

Published: November 2009

AI Article Synopsis

  • Breast cancer during pregnancy is rare but creates challenges for patients and doctors due to limited studies on diagnosis and treatment.
  • Women diagnosed with breast cancer in pregnancy typically exhibit similar characteristics to women without pregnancy, but staging may face limitations.
  • Treatments like surgery can proceed similarly to non-pregnant patients, while chemotherapy is permitted after the first trimester, but radiotherapy and other systemic treatments should wait until after delivery.

Article Abstract

Breast cancer in pregnancy is an uncommon situation but poses dilemmas for patients and their physicians. There is a paucity of prospective studies regarding diagnosis and treatment of breast cancer during pregnancy. Women diagnosed with breast cancer during pregnancy have similar disease characteristics to age-matched controls. Current evidence suggests that diagnosis may be carried out with limitations regarding staging. Surgical treatment may be performed as for non-pregnant women. Radiotherapy and endocrine or antibody treatment should be postponed until after delivery. Chemotherapy is allowed after the first trimester. Physicians should be aggressive in the workup of breast symptoms in the pregnant population to expedite diagnosis and allow multidisciplinary treatment without delay.

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http://dx.doi.org/10.1016/j.ejogrb.2009.06.030DOI Listing

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