Exponential principal component analysis (e-PCA) has been proposed to reduce the dimension of the parameters of probability distributions using Kullback information as a distance between two distributions. It also provides a framework for dealing with various data types such as binary and integer for which the Gaussian assumption on the data distribution is inappropriate. In this paper, we introduce a latent variable model for the e-PCA. Assuming the discrete distribution on the latent variable leads to mixture models with constraint on their parameters. This provides a framework for clustering on the lower dimensional subspace of exponential family distributions. We derive a learning algorithm for those mixture models based on the variational Bayes (VB) method. Although intractable integration is required to implement the algorithm for a subspace, an approximation technique using Laplace's method allows us to carry out clustering on an arbitrary subspace. Combined with the estimation of the subspace, the resulting algorithm performs simultaneous dimensionality reduction and clustering. Numerical experiments on synthetic and real data demonstrate its effectiveness for extracting the structures of data as a visualization technique and its high generalization ability as a density estimation model.
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http://dx.doi.org/10.1109/TNN.2009.2029694 | DOI Listing |
Phys Rev Lett
July 2024
Fujian Key Laboratory of Quantum Information and Quantum Optics, Fuzhou University, Fuzhou 350116, China.
Cat-state qubits formed by photonic cat states have a biased noise channel, i.e., one type of error dominates over all the others.
View Article and Find Full Text PDFBioinformatics
June 2024
School of Software Engineering, Beijing Jiaotong University, Beijing 100044, China.
Motivation: The identification of cancer subtypes plays a crucial role in cancer research and treatment. With the rapid development of high-throughput sequencing technologies, there has been an exponential accumulation of cancer multi-omics data. Integrating multi-omics data has emerged as a cost-effective and efficient strategy for cancer subtyping.
View Article and Find Full Text PDFMagn Reson Med
October 2024
Magnetic Resonance Methodology, Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland.
Purpose: Prostate tissue has a complex microstructure, mainly composed of epithelial and stromal cells, and of extracellular (acinar-luminal) spaces. Diffusion-weighted MR spectroscopy (DW-MRS) is ideally suited to explore complex microstructure in vivo with metabolites selectively distributed in different subspaces. To date, this technique has been applied to brain and muscle.
View Article and Find Full Text PDFNat Commun
May 2024
James Franck Institute, University of Chicago, Chicago, IL, 60637, USA.
Magn Reson Med
October 2024
Centre de Résonance Magnétique des Systèmes Biologiques, UMR5536, CNRS, University Bordeaux, Bordeaux, France.
Purpose: To accelerate whole-brain quantitative mapping in preclinical imaging setting.
Methods: A three-dimensional (3D) multi-echo spin echo sequence was highly undersampled with a variable density Poisson distribution to reduce the acquisition time. Advanced iterative reconstruction based on linear subspace constraints was employed to recover high-quality raw images.
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