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| http://dx.doi.org/10.1016/j.jaci.2009.07.046 | DOI Listing |
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Perinatal Mental Health Disorders and Resilience in Patients with Fetal Anomalies.
Am J Perinatol
January 2025
Division of Pediatric Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
Objective: Pregnant women face heightened vulnerability to mental health disorders (MHDs). There remains a lack of data during the antenatal period, particularly for high-risk subpopulations such as those with fetal anomalies. Understanding the psychological impact of women receiving a fetal anomaly diagnosis is crucial, as it can lead to MHDs.
View Article and Find Full Text PDFPharmacokinetic modeling of prenatal vitamin D exposure and the impact on offspring asthma and pulmonary function.
Biomed Pharmacother
January 2025
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:
Gestational 25-hydroxyvitamin D (25[OH]D) is important in fetal lung development and may influence offspring respiratory outcomes, making accurate exposure assessment essential to understand clinical associations. Therefore, we used the combined data from two large RCTs investigating prenatal vitamin D supplementation, which included early and late prenatal 25(OH)D measurements, to refine a population pharmacokinetic model of vitamin D-25(OH)D and estimate individual area under the curve (AUC) Z-scores. The primary outcome was physician-diagnosed offspring asthma/wheezing at ages 3 and 6 years, and lung function, as a secondary outcome, was evaluated by spirometry at the ages 6 and 8 years.
View Article and Find Full Text PDFMaternal urinary levels of PAH metabolites, umbilical cord blood telomere length and anthropometric indices in newborns.
Ecotoxicol Environ Saf
January 2025
Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. Electronic address:
The existing evidence indicating that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with a range of adverse outcomes, including alterations in anthropometric indices, underscores the need for further investigation into the underlying mechanisms. This study aims to examine the effects of prenatal PAH exposure on anthropometric indices and telomere length (TL), as well as to explore whether changes in TL can serve as a predictor of alterations in anthropometric measures. The study was conducted in Shenyang, China, with 2460 pregnant women participating between 2022 and 2023.
View Article and Find Full Text PDFThird-trimester resolution of low placentation and risk of postpartum hemorrhage.
Eur J Obstet Gynecol Reprod Biol
January 2025
Montefiore Medical Center/Albert Einstein College of Medicine, Division of Fetal Medicine and Ultrasound, Department of Obstetrics and Gynecology and Women's Health.
Objective: Low placentation is associated with increased risk of postpartum hemorrhage (PPH). There is a paucity of data on the association between second trimester low placentation that later resolves, and PPH. Our objective was to investigate the association of resolved low placentation and other prenatal ultrasound markers, and PPH with delivery.
View Article and Find Full Text PDFEarlier pregnancies in nulliparous women with current father and lower risks for preeclampsia and low-birth weight newborns.
J Reprod Immunol
January 2025
Institute of Clinical Medicine, School of Medicine, University of Eastern Finland, Kuopio, Finland; Department of Obstetrics and Gynaecology, Kuopio University Hospital, PL 100, Kuopio 70029, Finland. Electronic address:
New paternity has been related to placenta-associated complications in pregnancy. We evaluated whether a lack of earlier pregnancies or deliveries with a current father are associated with the pregnancy, prenatal, and early neonatal outcomes after controlling for the most common maternal confounders in prospective birth cohort study. An online questionnaire was used to survey 4459 pregnant women from the Kuopio Birth Cohort in their third trimester.
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