Drug dosing in the elderly patients with chronic kidney disease.

Clin Geriatr Med

Division of Nephrology & Hypertension, Oregon Health and Science University, 3314 SW US Veterans Hospital Road, Portland, OR 97201, USA.

Published: August 2009

AI Article Synopsis

  • Chronic kidney disease affects nearly 19 million people in the U.S., particularly impacting older adults who are at increased risk for kidney failure and renal impairment.
  • Most kidney diseases are chronic and typically present in late life, with factors like ischemic events and exposure to harmful medications heightening risk.
  • Care providers need to be cautious when prescribing medications to elderly patients with chronic kidney disease due to the complexities of managing their conditions.

Article Abstract

Chronic kidney disease is a common disorder that affects many patients with a prevalence approaching 19 million people in the United States. Kidney failure and renal impairment is a common occurrence in the geriatric population. Most types of kidney diseases are chronic conditions and frequently manifest at the late stages of life. Epidemiologic studies suggest that older patients are at a greater risk for renal failure if the kidney experiences insults from ischemia or exposure to pharmacologic and diagnostic nephrotoxins. Pharmacologic management of most common diseases in elderly individuals is a difficult task, particularly in older individuals with chronic kidney disease. Thus, primary care providers must proceed with caution when prescribing drugs for elderly patients with kidney disease.

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Source
http://dx.doi.org/10.1016/j.cger.2009.04.004DOI Listing

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