AI Article Synopsis
- The study examined the link between the severity of acute pancreatitis and intra-abdominal pressure (IAP) considering that increased IAP can lead to abdominal compartment syndrome.
- A total of 25 patients with acute severe pancreatitis were analyzed, focusing on their Ranson criteria, Apache II score, and IAP measurements.
- Results indicated a strong positive correlation (correlation coefficient of 0.781) between the Apache II score and IAP, suggesting that higher severity of pancreatitis is associated with increased abdominal pressure.
Article Abstract
Background: Intra-abdominal pressure rises in some circumstances and can cause abdominal compartment syndrome. Severe acute pancreatitis frequently causes abdominal compartment syndrome.
Objective: Our objective was to identify the relationship between severity of pancreatitis and abdominal pressure.
Material And Methods: From September 2001 to September 2002, all patients with acute severe pancreatitis were included in the study; exclusion was effected with history of abdominal surgery for pancreatitis or ventral hernias. In all patients, we carried out laboratory tests to establish ranson criteria, Apache II score, and indirect measurement of abdominal pressure. Lineal regression and chi-square test were done.
Results: A total of 25 patients was included, 10 men and 15 women, average age 49.4 years, 11 with mild pancreatitis and 14 with severe acute pancreatitis. Abdominal pressure was 2 to 19 cm H2O. On statistic analysis, there was strong positive correlation between Apache II score and IAP and 0.781 of correlation coefficient and 99.5% confidence interval.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Unusual Causes of Death Due to Constipation.
Am J Forensic Med Pathol
December 2024
Forensic Pathology Unit, Royal Darwin Hospital, Darwin, Northern Territory and College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Constipation is found in individuals with intellectual disabilities, autism, and cerebral palsy. Although generally a benign condition, it may lead to life-threatening intestinal obstruction, with or without volvulus, or to stercoral ulceration with enteritis and/or perforation. Two unusual cases of lethal chronic constipation are reported to demonstrate other very rare fatal mechanisms that may occur.
View Article and Find Full Text PDFDosing optimisation of intravenous lidocaine in patients with class 1-3 obesity by population pharmacokinetic analysis.
Anaesthesia
January 2025
Department of Anaesthesia and Perioperative Medicine, The Royal Brisbane and Women's Hospital, Brisbane, Australia.
Article Synopsis
- The study focused on developing an optimized lidocaine dosing regimen for obese patients during surgery, highlighting the need for more effective pain management.
- Researchers gathered data from 30 patients, measuring plasma levels of lidocaine and its metabolites to create a pharmacokinetic model.
- The findings suggested that current dosing was often inadequate, but an adjusted regimen could improve the likelihood of reaching therapeutic drug concentrations.
Giant Inguino-Scrotal Hernia With Loss of Domain: Surgical Report and Literature Review.
Cureus
November 2024
Surgery and Transplantation, Universitätsspital Zürich, Zürich, CHE.
The surgical repair of giant inguinal hernias with loss of domain, defined as the relocation of the majority of the intestine into the hernia sac, poses a significant challenge. In the majority of cases, a combination of different surgical techniques with the placement of multiple meshes is necessary to achieve reduction of such complex hernias. The reduction of chronic giant hernias can increase the risk of abdominal compartment syndrome or cardiopulmonary complications.
View Article and Find Full Text PDFDevelopment of a New Score Based on Image Defined Risk Factors to Standardize Surgical Risk in Neuroblastoma Resection - A SIOPEN Collaborative Study.
J Pediatr Surg
December 2024
Pediatric Surgery, Dipartimento di Medicina di Precisione e Rigenerativa a Area Jonica, Azienda Ospedaliera-Universitaria Consorziale Ospedale Pediatrico Giovanni XXIII, Bari, Italy.
Background And Aims: Image Defined Risk Factors (IDRFs) assess surgical risk in neuroblastoma (NB) and guide neoadjuvant therapy. Despite chemotherapy IDRFs may persist in 70 % of cases. Several studies have suggested that not all IDRFs hold equal significance and that the presence of an IDRF does not inherently signify unresectability.
View Article and Find Full Text PDFVaginal Orthosis After Native Tissue Reconstructive Surgery: Design and Phase 0.
Urogynecology (Phila)
December 2024
From the Division of Urogynecology and Reconstructive Pelvic Surgery, University of Alabama at Birmingham, Birmingham, AL.
Importance: Pelvic organ prolapse recurrence following native tissue repair occurs with composite failure rates of 9-19% within 12 months, predominantly involving apical/anterior compartments. Objective The objective of this study was to develop a novel vaginal orthosis (NVO) device prototype through an iterative design process based on investigator and user feedback.
Study Design: The NVO was designed based on pelvic floor biomechanical principles to mitigate unopposed intra-abdominal pressure of the anterior vagina by absorbing and redirecting intra-abdominal forces to the levator ani and tailored to accommodate postoperative vaginal caliber and axis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!