A colorimetric and fluorescent merocyanine-based probe for biological thiols.

Org Biomol Chem

Department of Chemistry and The Key Laboratory of Analytical Sciences of MOE, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, PR China.

Published: October 2009

A new "dual-mode" chromogenic and fluorescent turn-on probe (2) for the selective sensing of biological thiols is reported. In MeOH-H(2)O cosolvent at physiological pH 7.40 (MeOH-H(2)O = 3:7), biological thiols cleave the 2,4-dinitrobenzenesulfonyl group to release the chromo- and fluorophore merocyanine (3).

Download full-text PDF

Source
http://dx.doi.org/10.1039/b909760kDOI Listing

Publication Analysis

Top Keywords

biological thiols
12
colorimetric fluorescent
4
fluorescent merocyanine-based
4
merocyanine-based probe
4
probe biological
4
thiols "dual-mode"
4
"dual-mode" chromogenic
4
chromogenic fluorescent
4
fluorescent turn-on
4
turn-on probe
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!