AI Article Synopsis
- The study evaluates the long-term oncological outcomes of laparoscopic radical nephrectomy for kidney cancer, with a follow-up period averaging 11.2 years.
- A total of 73 patients underwent the procedure, with cancer-specific survival rates hitting 92% at 10 years and 78% at 12 years, showcasing impressive long-term results.
- The authors conclude that laparoscopic surgery for renal cell carcinoma provides excellent outcomes, comparable to traditional open surgeries, despite some patients developing metastatic disease.
Article Abstract
Purpose: We present oncological outcomes at a followup of 10 years or greater after laparoscopic radical nephrectomy for cancer.
Materials And Methods: Between February 1994 and March 1999 a total of 73 laparoscopic radical nephrectomies were performed by 2 surgeons for pathologically confirmed renal cell carcinoma. Data were obtained from patient charts, radiographic reports, telephone followup and a check of the Social Security Death Index.
Results: Mean followup was 11.2 years (range 10 to 15). Each patient completed a minimum 10-year followup. Mean patient age at surgery was 60 years. Mean tumor size on computerized tomography was 5 cm (range 1.7 to 13). Pathological stage was pT1a in 41% of cases, pT1b in 30%, pT2 in 15%, pT3a in 10%, pT3b in 3% and pT4 in 1%. High grade tumors (Fuhrman 3 or greater) were present in 18 cases (28%). A positive surgical margin occurred in 1 case. Actual 10-year overall, cancer specific and recurrence-free survival rates were 65%, 92% and 86%, respectively. Overall, cancer specific and recurrence-free survival rates at 12 years were 35%, 78% and 77%, respectively. At a mean of 67 months 10 patients (14%) had metastatic disease, of whom 8 (11%) died.
Conclusions: Long-term oncological outcomes after laparoscopic radical nephrectomy for renal cell carcinoma are excellent and appear comparable to those of open surgery.
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| http://dx.doi.org/10.1016/j.juro.2009.07.047 | DOI Listing |
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