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Pseudobulbar Affect Correlates with Mood Symptoms and Low Quality of Life in Patients with Parkinson's Disease: A Comprehensive Cross-Sectional Study.
Sisli Etfal Hastan Tip Bul
December 2024
Department of Neurology, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Türkiye.
Objectives: Despite being recognized for a long time as a characteristic of Parkinson's disease (PD), pseudobulbar affect (PBA) is still a symptom that is underdiagnosed and undertreated. This study aimed to assess the association between PBA and various mood disturbances, as well as the impact on quality of life in PD patients.
Methods: Sixty-eight patients with PD were enrolled in this study.
Epidemiology of extended-spectrum beta-lactamase producing Enterobacteriaceae in Qatar: A 3-year hospital-based study.
Front Antibiot
September 2022
Communicable Disease Center, Hamad Medical Corporation, Doha, Qatar.
Background: The incidence of ESBL infections is exponentially increasing with variable prevalence among geographical areas and treatment settings. Identifying local prevalence rate and patient-related factors will help in earlier recognition and initiation of appropriate antibiotics treatment of patients with ESBL infections.
Methods: Retrospective analysis of all positive cultures for ESBL producing Enterobacteriaceae collected in Al-Khor hospital from January 2010 to December 2012.
Open lower limb fracture reconstruction in the elderly population: the experience of a major trauma centre.
Eur J Trauma Emerg Surg
January 2025
Department of Plastic and Reconstructive Surgery, Addenbrookes Hospital, Hills Rd, Cambridge, CB2 0QQ, UK.
Purpose: Management of the elderly patients presenting with open lower limb fractures is challenging due to physiological changes and pre-existing co-morbidities. The aim of this study was to assess the compliance with the British Orthopaedic Association's Standards for Trauma Number 4 (BOAST 4) guidelines in this patient group.
Methods: The study included a retrospective analysis of all the patients aged > 65 years old admitted with open lower limb fracture between 2017 and 2019 to a major trauma centre (MTC) in East of England.
Demographic and clinical predictors of response and remission in the treatment of major depressive disorder with ketamine and esketamine: A systematic review.
Psychiatry Res
January 2025
Department of Psychiatry, University Medical Center Groningen, Groningen, the Netherlands.
Accumulating evidence supports the efficacy of (es)ketamine in the treatment of major depressive disorder (MDD), particularly treatment-resistant depression (TRD). Yet around 50% of the individuals with TRD do not respond to (es)ketamine. Elucidating predictors of response and remission could improve treatment outcomes at the individual level by defining subpopulations that are most likely to benefit from (es)ketamine.
View Article and Find Full Text PDFDental caries and related factors in the elderly of the Azar cohort population: A cross-sectional study.
PLoS One
January 2025
Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Objective: Oral health is often overlooked among the elderly due to the numerous comorbidities prevalent in this population. However, oral health significantly influences quality of life by affecting both general health and psychological well-being. The present study aimed to assess dental caries in elderly individuals using the DMFT index (decayed, missing, and filled teeth) and to explore its relationship with various factors based on data from the Azar cohort study in Iran.
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