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Alleviating effects of Nigella sativa supplements on biomarkers of inflammation and oxidative stress: Results from an umbrella meta-analysis.
Prostaglandins Other Lipid Mediat
December 2024
Department of Internal Traditional Chinese Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. Electronic address:
Several meta-analyses have examined the effect of Nigella sativa (N. Sativa) supplementation on inflammatory and oxidative markers, with conflicting results. So, the current study evaluated the effect of N.
View Article and Find Full Text PDFAntibacterial and Anti-biofilm Effects of Thymoquinone Against Carbapenem-Resistant Uropathogenic .
Indian J Microbiol
December 2024
Department of Medical Sciences, Graduate School, Soonchunhyang University, Asan, Chungnam 31538 Republic of Korea.
Carbapenem antibiotics are widely used for their broad antibacterial effects, but the emergence of carbapenem-resistant has recently become a global problem. To solve this problem, research is needed to find compounds that increase antibiotic activity. Therefore, this study aimed to validate the antibacterial and anti-biofilm effects, as well as the inhibition of gene expression of thymoquinone, an extract of commonly used as a spice in many dishes.
View Article and Find Full Text PDFExploring the optical properties of metal-modified melanin following ultraviolet irradiation: An experimental and theoretical study using density functional theory.
Heliyon
April 2024
Physics Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 13318, Saudi Arabia.
Melanin has an important function to protect humans from sunlight because of its broad spectrum of light absorption. This characteristic varies according to the nature of absorption and the amount of melanin manufactured. This study focused on UV-Vis absorption of melanin doped with (Fe, Co, Zn) ions.
View Article and Find Full Text PDFEffect of ozonation on the phytochemicals of black seed oil and its anti-microbial, anti-oxidant, anti-inflammatory, and anti-neoplastic activities in vitro.
Sci Rep
December 2024
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.
Black seed has been applied for several decades to cure an extensive variety of illnesses and ailments. In this report, the chemical profile of both crude and ozonized black seed oil was assessed after the oil was exposed to 0 to 5 L/minute of ozone for four hours. The in vitro effects of black seed oil following being exposed to ozone including antimicrobial properties versus Bacillus cereus (ATCC11778), Staphylococcus aureus (ATCC6538), Escherichia coli (ATCC8739), Salmonella typhi (ATCC 6539), and Klebsiella pneumoniae (ATCC13883), Candida albicans (ATCC10221), and Aspergillus niger (ATCC16888).
View Article and Find Full Text PDFInhibitory Effect of L. Extracts on SARS-COV-2 Spike Protein-ACE2 Interaction.
Curr Ther Res Clin Exp
August 2024
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Ethnopharmacological Relevance: A catastrophic outbreak of severe acute respiratory syndrome (SARS-CoV-2; Coronavirus disease-19; COVID-19) was first detected in Wuhan, Hubei Province, China, in December 2019. Many experimental and clinical studies have focused on the effectiveness of medicinal plants such as (NS) in combating SARS-CoV-2. In this study, we aimed to evaluate the effect of NS seed extract on SARS-CoV-2 spike protein (S1)-angiotensin-converting enzyme 2 (S-ACE2) interaction.
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