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Resting-State EEG Oscillations in Amyotrophic Lateral Sclerosis (ALS): Toward Mechanistic Insights and Clinical Markers.
J Clin Med
January 2025
Faculty of Physical Culture and Health, Institute of Physical Culture Sciences, University of Szczecin, Al. Piastów 40B blok 6, 71-065 Szczecin, Poland.
Amyotrophic lateral sclerosis (ALS) is a complex, progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain, brainstem, and spinal cord. Several neuroimaging techniques can help reveal the pathophysiology of ALS. One of these is the electroencephalogram (EEG), a noninvasive and relatively inexpensive tool for examining electrical activity of the brain with excellent temporal precision.
View Article and Find Full Text PDFMechanical Strain of Corneal Epithelium Influences the Expression of Genes Implicated in Keratoconus.
Invest Ophthalmol Vis Sci
January 2025
Wilmer Eye Institute, Johns Hopkins Medical Institute, Baltimore, Maryland, United States.
Purpose: Although mechanical injury to the cornea (e.g. chronic eye rubbing) is a known risk factor for keratoconus progression, how it contributes to loss of corneal integrity is not known.
View Article and Find Full Text PDFEffect of ethnicity and other sociodemographic factors on attendance at ophthalmology appointments following referral from a Diabetic Eye Screening Programme: a retrospective cohort study.
BMJ Open Ophthalmol
January 2025
Population Health Research Institute, City St George's, University of London, London, UK
Background/aims: To examine the association between sociodemographic characteristics and attendance at Hospital Eye Service (HES) referrals from the Diabetic Eye Screening Programme (DESP), in a large, ethnically diverse urban population.
Methods: Retrospective cohort study (4 January 2016-12 August 2019) of people with diabetic retinopathy (DR) referred from an English DESP to a tertiary referral eye hospital. We conducted a multivariable logistic regression with attendance as the primary outcome, controlling for age, sex, ethnicity, Index of Multiple Deprivation, best eye visual acuity and baseline DR grade.
Actual dishonest behaviour versus self-perception as an honest student: Real time observational and self-report study.
Nurse Educ Today
January 2025
Shamir Academic School of Nursing, Hebrew University in Jerusalem, Israel; Ministry of Health, Israel. Electronic address:
Background: Academic dishonesty poses significant challenges in educational settings, particularly among nursing students. Efforts to mitigate this issue through pedagogical and technological approaches have seen limited success. Diverse theoretical explanations for academic dishonesty underscore the need for further exploration of this multifaceted phenomenon.
View Article and Find Full Text PDF"Undisciplined and a Moral Danger": Fright, Idleness and Immorality as Attributions of "Imbecile Children" in Late Victorian and Edwardian Britain.
J Hist Behav Sci
January 2025
UCL, London, UK.
From the second half of the nineteenth-century treatment of "imbecile" children in Britain underwent significant change. Examining the period from 1870 to 1920 when imbecility became a discrete category, and a matter of concern in policy and practice, this paper focuses on conceptualizations around fright, idleness, morality, and parental mental state as behavioral, emotional, and psychological causes and attributions of "imbecility" in children. I view this in light of the Victorian emotional culture of "care and control," which was driven by a shift in cost-cutting and fear of the impact of "imbecile children" on society, justifying exclusions, defining boundaries, and driving change.
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