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Monitoring the immune response of macrophages in tuberculous granuloma through the expression of CD68, iNOS and HLA-DR in naturally infected beef cattle.
BMC Vet Res
October 2023
Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Assuit University, Assiut, Egypt.
Bovine tuberculosis still represents a universal threat that creates a wider range of public and animal health impacts. One of the most important steps in the pathogenesis of this disease and granuloma formation is the phagocytosis of tuberculous bacilli by macrophages. Mycobacteria replicate in macrophages, which are crucial to the pathophysiology of mycobacterial infections; however, scarce information is available about the dynamics of the granuloma-stage immunological response.
View Article and Find Full Text PDFRecovery rates of mycobacterium from suspected extra-pulmonary tuberculosis patients using liquid culture at a tertiary referral centre of India.
Indian J Tuberc
April 2023
Department of Thoracic Surgery and Surgical Anatomy, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi 110030, India.
Tuberculosis still remains a serious public health problem in developing countries. Rapid isolation of mycobacteria is critical for accurate diagnosis and management of tuberculosis. In the present study BACTEC MGIT 960 system was evaluated against Lowenstein Jensen (LJ) medium for isolation of mycobacteria from different extra-pulmonary specimens (N = 371).
View Article and Find Full Text PDF[Investigation of Efflux Pump Genes in Resistant Mycobacterium tuberculosis Complex Clinical Isolates Exposed to First Line Antituberculosis Drugs and Verapamil Combination].
Mikrobiyol Bul
April 2023
Mersin University Faculty of Medicine, Department of Medical Microbiology, Mersin, Türkiye.
Tuberculosis (TB) is caused by Mycobacterium tuberculosis, still one of the most common life-threatening infectious diseases worldwide. Although drug resistance in M.tuberculosis is mainly due to spontaneous chromosomal mutations in genes encoding drug target or drug activating enzymes, the resistance cannot be explained only by these mutations.
View Article and Find Full Text PDFBacterial Lesions of the Oral Mucosa.
Oral Maxillofac Surg Clin North Am
May 2023
Department of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro (UFRJ), Brazil.
Article Synopsis
- * Diagnosis of these uncommon infections is often delayed due to their unusual nature, which can lead to more severe health issues and increased risk of spreading the infection.
- * It’s important for healthcare providers to be aware of these rare but serious infections to ensure timely treatment when they occur.
Extra-pulmonary tuberculosis still remains an important differential diagnosis for chronic musculoskeletal ailments in developing countries like India and may involve any part of the body without characteristic systemic features. We are presenting a rare case of a four-year-old female child, who came to our tertiary-care hospital with chief complaints of pain in the left foot along with a gradually increasing swelling over the dorsum of the foot for the past five months. There was no history of trauma or constitutional symptoms.
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