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[Pseudo-conduction block in nonsystemic vasculitic neuropathy]. | LitMetric

[Pseudo-conduction block in nonsystemic vasculitic neuropathy].

An Sist Sanit Navar

Servicio de Neurofisiología Clínica, Hospital Virgen del Camino, Pamplona, 31008, Spain.

Published: April 2010

AI Article Synopsis

  • Nonsystemic vasculitic neuropathy (NSVN) is an inflammatory condition affecting small blood vessels supplying nerves, often presenting as mononeuritis multiplex.
  • A case of a 36-year-old woman with NSVN showed initial symptoms of tingling and weakness, with neurophysiological tests revealing low amplitude in the right median nerve and evidence of axonal damage.
  • The study highlights that early ischemic nerve damage can cause misleading patterns in nerve conduction studies, indicating the need for repeated tests to accurately assess changes over time in suspected vasculitic neuropathies.

Article Abstract

Summary: Introduction. Nonsystemic vasculitic neuropathy (NSVN) is an inflammatory disorder of the vasa nervorum which usually is expressed as a mononeuritis multiplex. We present a patient with NSVN with histological confirmination focused on the neurophysiological findings at the early stages.

Case Report: A 36 years-old woman presented with paresthesia and weakness in her right hand followed by left footdrop. The first neurophysiologic examination showed low amplitude of the right median nerve (RMN) CMAP with proximal stimulation. A second examination showed signs of axonal damage in several nerves, including the RMN.

Conclusions: The acute ischemic damage of a nerve can give a pattern of conduction block in the electroneurographic study as in the RMN of the presented case. This phenomenon is referred as "pseudo-conduction block", since it is transient and evolves towards a definite pattern of axonal neuropathy. When a vasculitic neuropathy is suspected, repeated neurophysiologic studies are necessary in order to ensure a proper (appropriate) characterization of the lesional patterns.

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Source
http://dx.doi.org/10.23938/ASSN.0168DOI Listing

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