This study investigated the effects of guarana seed extract (GSE) on an anti-allergic mechanism. GSE orally administered inhibited the anti-dinitrophenol IgE-induced passive cutaneous anaphylaxis reaction in mice. Furthermore, it inhibited the degranulation of rat basophilic leukemia RBL-2H3 cells. It had no cytotoxicity on RBL-2H3 cells. These results show that GSE is a candidate for effective therapeutic material for allergic diseases.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1271/bbb.90205 | DOI Listing |
Publication Analysis
Top Keywords
effects guarana
8
guarana seed
8
seed extract
8
passive cutaneous
8
cutaneous anaphylaxis
8
rbl-2h3 cells
8
inhibitory effects
4
extract passive
4
anaphylaxis mast
4
mast cell
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!