Objective: Several studies have shown a reduction in pulmonary artery pressure (PAP) after adenoidectomy in children suffering form upper airway obstruction caused by adenoid hypertrophy (AH). However, it is not clear whether this would be significantly reflected on right ventricle output (RVO).
Methods: Our aim was to determine if there were any detectable changes in RV performance parameters after adenoidectomy in children with AH. Thirty children with AH (female/male: 11/19) aged between 2.5 and 12 years (median: five years) were included in this study. Adenoidectomy was performed under sinuscopic guide using adenoid curette and microdebrider. All children were examined by echocardiography one day before and one month after adenoidectomy. Velocity time integral of tricuspid valve flow (VTItv) and pulmonary valve flow (VTIpa); E/A ratio of tricuspid valve flow; RV end-diastolic diameter (RVEDd) and left ventricle fraction shortening (FS) were measured. Heart rate (HR) was also recorded.
Results: Preoperatively VTItv, VTIpa, E/A ratio, RVEDd, FS, and HR were 18.6+/-3.0 cm, 20.8+/-3.1 cm, 1.21+/-0.31, 11.5+/-2.1 mm, 35.1+/-4.3%, and 112+/-19, respectively. Postoperatively VTItv, VTIpa, E/A ratio, RVEDd, FS, and HR were 21.5+/-2.5 cm, 24.4+/-4.3 cm, 1.44+/-0.32, 9.3+/-2.6 mm, 33.9+/-3.5%, and 104+/-28, respectively. There were significant differences between preoperative and postoperative VTItv (p=0.03), VTIpa (p=0.01), E/A ratios (p=0.04), and RVEDd (p=0.01). FS and HR were not significantly different.
Conclusions: This study illustrated that in children suffering from AH, relieving upper airway obstruction by adenoidectomy may result in improvement of RV filling and RVO, associated with the reduction in PAP.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijporl.2009.08.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Focused ion beam (FIB) prepared microtextured microneedle array capable of delivering drugs through punctured skin.
Sci Rep
December 2024
School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, China.
Microtextured microneedles are tiny needle-like structures with micron-scale microtextures, and the drugs stored in the microtextures can be released after entering the skin to achieve the effect of precise drug delivery. In this study, the skin substitution model of Ogden's hyperelastic model and the microneedle array and microtexture models with different geometrical parameters were selected to simulate and analyse the flow of the microtexture microneedle arrays penetrating the skin by the finite-element method, and the length of the microneedles was determined to be 200 μm, the width 160 μm, and the value of the gaps was determined to be 420 μm. A four-pronged cone was chosen as the shape of microneedles, and a rectangle was chosen as the shape of the drug-carrying microneedle.
View Article and Find Full Text PDFImpact of magnetorheological fluid composition on their behaviour in gradient pinch mode.
Sci Rep
December 2024
Faculty of Mechanical Engineering, Brno University of Technology, Technická 2, Brno, Czechia, Czechia.
Magnetorheological (MR) fluids can be utilized in one of the fundamental operating modes of which the gradient pinch mode has been the least explored. In this unique mode non-uniform magnetic field distributions are taken advantage of to develop a so-called Venturi-like contraction in MR fluids. By adequately directing magnetic flux the material can be made solidified in the regions near the flow channel wall, thus creating a passage in the middle of the channel for the fluid to pass through.
View Article and Find Full Text PDFFully 4D-Printed Near-Infrared-Actuated Lab-on-Valve Solid-Phase Extraction Devices.
Anal Chem
December 2024
Department of Chemistry, National Chung Hsing University, Taichung City 402202, Taiwan, ROC.
Four-dimensional printing (4DP) technologies can expand the functionality of stimuli-responsive devices to enable the integration of multiple stimuli-responsive parts into a compact device. Herein, we used digital light processing three-dimensional printing technique, flexible photocurable resins, and photocurable resins of the temperature-responsive hydrogels comprising -isopropylacrylamide (NIPAM), ,'-methylenebis(acrylamide) (MBA), and graphene for 4DP of a lab-on-valve (LOV) solid-phase extraction (SPE) device. This device featured flow manifolds and a monolithic packing connected by four near-infrared (NIR)-actuated temperature-responsive switching valves composed of a poly(NIPAM/MBA) (PNM) ball pushing a flexible membrane.
View Article and Find Full Text PDFPlanning transcatheter pulmonary valve implantation in the dysfunctional native RVOT: A semi-automated pipeline for dynamic analysis based on 4D-CT imaging.
Comput Methods Programs Biomed
December 2024
Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy.
Background And Objective: Dysfunction of the right ventricular outflow tract (RVOT) is a common long-term complication following surgical repair in patients with congenital heart disease. Transcatheter pulmonary valve implantation (TPVI) offers a viable alternative to surgical pulmonary valve replacement (SPVR) for treating pulmonary regurgitation but not all RVOT anatomies are suitable for TPVI. To identify a suitable landing zone (LZ) for TPVI, three-dimensional multiphase (4D) computed tomography (CT) is used to evaluate the size, shape, and dynamic behavior of the RVOT throughout the cardiac cycle.
View Article and Find Full Text PDFSpns1-dependent endocardial lysosomal function drives valve morphogenesis through Notch1-signaling.
iScience
December 2024
Department of Developmental Biology and Regeneration, Institute of Anatomy, University of Bern, 3012 Bern, Switzerland.
Autophagy-lysosomal degradation is a conserved homeostatic process considered to be crucial for cardiac morphogenesis. However, both its cell specificity and functional role during heart development remain unclear. Here, we introduced zebrafish models to visualize autophagic vesicles and track their temporal and cellular localization in the larval heart.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!