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Phase I study of concurrent selective lymph node late course accelerated hyper-fractionated radiotherapy and Capecitabine, Cisplatin for locally advanced esophageal squamous cell carcinoma. | LitMetric
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Phase I study of concurrent selective lymph node late course accelerated hyper-fractionated radiotherapy and Capecitabine, Cisplatin for locally advanced esophageal squamous cell carcinoma.

Bao-sheng Li Tao Zhou Zhong-tang Wang Hong-sheng Li Hong-fu Sun Zhi-cheng Zhang Hai-qun Lin Yu-mei Wei He-yi Gong Wei Huang Yan Yi Li-ying Wang

Radiother Oncol

Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China.

Published: December 2009

Twelve patients with locally advanced esophageal squamous cell carcinoma were enrolled to evaluate the safety and efficacy of concurrent chemo-radiotherapy. Dose-limiting toxicity was mainly observed at Capecitabine 1500 mg. The maximum-tolerated dose/recommended dose of Capecitabine was 1000 mg. The Kaplan-Meier estimated overall l-year survival rate was 100%.

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http://dx.doi.org/10.1016/j.radonc.2009.08.002DOI Listing

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