AI Article Synopsis
- Hepatitis E virus (HEV) is a significant cause of hepatitis E infections in northern India, affecting both sporadic cases and outbreaks.
- A survey was conducted to test for IgG antibodies in serum samples from rural (1144 samples) and urban (1135 samples) populations, revealing that antibody levels increased with age.
- The urban population showed consistently higher exposure to HEV across age groups, suggesting that higher population density and shared water sources may put urban residents at a greater risk for infection.
Article Abstract
Hepatitis E virus (HEV) is an important cause of sporadic and epidemic hepatitis E infection in northern India. Sera, collected from different age groups in rural (n=1144) and urban (n=1135) areas using a probability proportional to size survey, were tested using an ELISA for IgG antibodies. Antibodies increased with age in both populations, but the urban population had higher exposure in all age groups (Mann-Whitney U test, P<0.001 for all age groups except children <5 years). These results indicate that urban populations with higher density and common water supplies may be at greater risk of hepatitis E.
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| http://dx.doi.org/10.1016/j.trstmh.2009.07.017 | DOI Listing |
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