Pulmonary ossification is an idiopathic disorder that presents with the formation of mature bone in the pulmonary parenchyma. This is a very rare entity that occurs in conjunction with busulfan therapy as well as with a number of diseases including chronic bronchitis, cystic fibrosis, congestive heart failure, myositis ossificans, and idiopathic interstitial fibrosis. It is usually seen in older age groups. We present a 4-year-old boy with massive ossification secondary to recurrent aspiration pneumonia. This is the first reported case of pulmonary ossification secondary to recurrent aspiration, and the first case in a child.
Download full-text PDF |
Source |
---|
Tuberk Toraks
December 2024
Department of Radiology, Tokat Gaziosmanpasa University Faculty of Medicine, Tokat, Türkiye.
Introduction: Diffuse pulmonary ossification (DPO) refers to the unusual formation of mature bone tissue within the lung parenchyma. It has been shown to be associated with a number of cardiac and chronic lung diseases. The relation between DPO and idiopathic pulmonary fibrosis (IPF) has been shown in the literature.
View Article and Find Full Text PDFClin Exp Metastasis
December 2024
Department of Musculoskeletal Oncology, Spine Tumor Center, Fudan University Shanghai Cancer Center, Shanghai, China.
Patient-derived tumor organoids (PDTOs) models have been widely used to investigate the response of primary cancer tissues to anti-cancer agents. Nonetheless, only few case study tried to establish PDTOs and test treatment response based on bone metastasis (BoM) tissues. Fresh BoM tissues were obtained from lung cancer (LC) patients who underwent spinal metastatic tumor surgery for PDTOs culture.
View Article and Find Full Text PDFOrphanet J Rare Dis
December 2024
Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 20133, Milan, Italy.
Introduction: Osteogenesis Imperfecta (OI) is characterised by brittle bones, severe skeletal deformities, low sleep quality, and restricted breathing. We aimed to distinguish how disease and obesity affect these results.
Methods: According to BMI, we considered four groups of peer adults (median age: 35.
J Orthop Surg Res
December 2024
Department of Orthopedics, Shenzhen Third People's Hospital, Shenzhen, 518112, China.
Background: Osteoporosis is a metabolic bone disease that has a common occurrence in postmenopausal women. Asperuloside (ASP) has been reported to exert anti-inflammatory and anti-oxidative effects in numerous diseases, such as rheumatoid arthritis and acute lung injury. However, whether ASP plays a role in osteoporosis has not been addressed.
View Article and Find Full Text PDFArkh Patol
December 2024
St. Petersburg Research Institute of Phthisiopulmonology, St. Petersburg, Russia.
Microscopic changes in the lung biopsies of 16 adult patients of both sexes without clear clinical symptoms are described. According to X-ray examination data, disseminated process in the lungs was diagnosed in 4 patients, interstitial pneumonia in 4, osteoplastic pneumopathy in 3, as well as tuberculosis, bronchiolitis and a number of others. Microscopic examination showed that the patients had various forms of petrification and ossification of the lungs, diagnosed clinically and radiologically in only 3 cases.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!