Clinical Case: A 58 year-old man with a known diagnosis of a large cell lung carcinoma, developed a progressive diplopia. His examination revealed a double oculomotor nerve palsy with dilated and poorly reactive pupils. A cranial magnetic resonance showed an unique and solitary lesion in the midbrain, which presumably affected to both oculomotor nucleus and fasciculus. There were not found additional extrathoracic manifestations.

Discussion: This case shows the possibility that a large cell lung carcinoma may cause a double oculomotor nerve palsy as the consequence of an isolated midbrain metastasis.

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http://dx.doi.org/10.4321/s0365-66912009000800006DOI Listing

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