Insulator elements mediate intra- and inter-chromosomal interactions. The insulator protein CCCTC-binding factor (CTCF) is important for insulator function in several animals but a report in BMC Molecular Biology shows that Caenorhabditis elegans, yeast and plants lack CTCF. Alternative proteins may have a similar function in these organisms.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776911 | PMC |
http://dx.doi.org/10.1186/jbiol165 | DOI Listing |
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