AI Article Synopsis
- The study explored how urinary follicle-stimulating hormone (FSH) affects the electrical activity of the myometrium in animals using signal-processing techniques.
- Thirty animals were divided into groups; one received a control solvent while others were treated with different FSH compounds after two normal estrous cycles.
- Results indicated that administering purified FSH and human menopausal FSH altered myoelectrical signal characteristics, reducing their power and spectral components, which suggests a role in promoting uterine relaxation.
Article Abstract
The aim of the study was to investigate the effects of urinary follicle-stimulating hormone (FSH) compounds on the electrical activity of myometrium using signal-processing techniques. Thirty animals were involved in the experiment. After two successive normal estrous cycles, 15 of these animals were put into three equal subgroups. Group 1 was the control; animals were given solvent. Groups 2 and 3 were treated with Urofollitropin and Menotropin, respectively. The other 15 animals were ovariectomized and subjected to the same protocol. Their uterine myoelectrical signals were recorded over a period of at least 3 min at a sampling frequency of 500 Hz, and analyzed through software assisted signal processing. The results show the power and some characteristic spectral components of myoelectrical signal were differentially reduced with the administration of highly purified urinary FSH and human menopausal FSH but significant differences were not detected between their histology. In conclusion, uterine myoelectrical signals change with administration of urinary FSH preparations. Human menopausal FSH and more precisely highly purified FSH suppress the spectral components and modify the power of the myoelectrical signals which provides uterine quiescence.
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| http://dx.doi.org/10.1093/molehr/gap076 | DOI Listing |
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