Adult laryngeal rhabdomyosarcoma: is aggressive treatment justified in all cases? A case report and review of the literature.

J Laryngol Otol

First Department of Otolaryngology-Head and Neck Surgery, National and Kapodistrian University of Athens, Hippokrateion Hospital, Athens, Greece.

Published: November 2009

Background: Adult laryngeal rhabdomyosarcomas are rare tumours commonly treated by laryngectomy.

Case Report: We present a case of subglottic laryngeal rhabdomyosarcoma in an elderly woman, treated by endoscopic resection.

Conclusion: Despite the fact that this tumour is traditionally treated aggressively, this approach is not supported by the literature. Due to the varying biological behaviour of this tumour in adults, we believe that conservative surgical procedures or combination therapies should be preferred, rather than total laryngectomy.

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0022215109990946DOI Listing

Publication Analysis

Top Keywords

adult laryngeal
8
laryngeal rhabdomyosarcoma
8
rhabdomyosarcoma aggressive
4
aggressive treatment
4
treatment justified
4
justified cases?
4
cases? case
4
case report
4
report review
4
review literature
4

Similar Publications

Introduction: The core objective of this study was to precisely locate metastatic lymph nodes, identify potential areas in nasopharyngeal carcinoma patients that may not require radiotherapy, and propose a hypothesis for reduced target volume radiotherapy on the basis of these findings. Ultimately, we reassessed the differences in dosimetry of organs at risk (OARs) between reduced target volume (reduced CTV2) radiotherapy and standard radiotherapy.

Methods And Materials: A total of 209 patients participated in the study.

View Article and Find Full Text PDF

Background: The purpose of this study was to identify the risk factors of severe orofacial and neck infections and the factors that could prevent them and reduce their severity.

Methods: A three-year prospective observational study was conducted from 8.15.

View Article and Find Full Text PDF

Early-stage laryngeal cancer (T1-T2) is commonly treated with organ-preserving techniques such as transoral laser microsurgery (TOLMS) or radiation therapy (RT), both providing comparable oncological outcomes but differing in functional results. Local recurrence occurs in approximately 10% of cases, making salvage surgery a crucial therapeutic option. This multi-institutional study investigates the efficacy of open partial horizontal laryngectomy (OPHL) as a salvage treatment, following recurrent laryngeal squamous-cell carcinoma (LSCC) after failed TOLMS.

View Article and Find Full Text PDF

Effect of propofol and ciprofol in patients undergoing bronchoscopy: protocol for a double-blind, randomised controlled trial.

BMJ Open

January 2025

Department of Anesthesiology and Perioperative medicine, Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, People's Republic of China

Introduction: Propofol is a fast-acting intravenous anaesthetic widely used for sedation and anaesthesia in gastrointestinal endoscopy, bronchoscopy, and the induction/maintenance of general anaesthesia in outpatients and inpatients; however, propofol has several undesirable effects, including injection pain, which affects the physical and mental health of patients, and cardiopulmonary depression, characterised by hypotension, bradycardia and apnea, which commonly occur in clinical practice. Ciprofol (HSK3486) is a propofol analogue with good clinical safety, high potency and some advantages over propofol, including lower injection pain and haemodynamic depression in patients undergoing gastroscopy and colonoscopy. This study aims to compare the impact of equivalent effective doses of propofol and ciprofol on haemodynamic changes in patients undergoing bronchoscopy under general anaesthesia.

View Article and Find Full Text PDF

[A case of extramedullary multiple myeloma with initial presentation of laryngeal symptoms].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

January 2025

Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai264000, China Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases,Yantai Key Laboratory of Otorhinolaryngologic Diseases, Yantai264000,China.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!